This paper inspects wetting rules of normal acid, alkanol and alkane on surfaces of stainless steel, platinum sheet and monocrystalline silicon and contrasts the influence on wetting effect by polarity difference. Experimental results show that for alkane not containing functional groups, the increasing of carbon number is beneficial to the enhancement of wetting effect; optimum wetting reagents for different surface present obvious selectivity, and for alkane, the wetting effect of stainless steel, platinum sheet and monocrystalline silicon is from good to bag in sequence. For organic alcohol and organic acid, the sequence is monocrystalline silicon, platinum sheet and stainless steel. Organic alcohol and organic acid are monocrystalline silicon, platinum sheet and stainless steel. Liquid solid interface polarity contrast shows that certain wetting difference is beneficial to the enhancement of wetting effect.
