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Bioinformatics is the intersection of computer science, statistics, molecular biology and genetics. It is one of the most important emerging research areas of the 21st century and has already attracted worldwide interest. It is clear that major initiatives are being undertaken which will establish Australia both as a vital link in the international bioinformatics community for research and development and also as an Asia-Pacific service for bioinformatics. This article briefly notes some groups carrying out bioinformatics research in Australia.
This paper presents a brief overview of intellectual property rights and the various areas in proteomics to which IP rights may be applicable. Technology transfer, including licensing and business agreements, is not covered in this paper. Instead, issues and complications that are related to national and overseas patent prosecution in this relatively new field would be discussed.
Competitive Positioning Strategies for Australian Biotech Companies A Road Map to Achieve Competitive Position in the Global Biotech Marketplace Part III — Australia: Current Position and Key Success Factors.
The article discusses about the potential of Australia and New Zealand biotechnology opportunities.
The article is a summary of the research done in GIS. It touches on the focus on systems and integrative biology and GIS's efforts in collaborating with international organizations.
University of Queensland Offers Biotech Scholarship to Indian Students.
Australian Government Contributes $50M to Walter and Eliza Hall Institute.
US Pharmacy Giant MedicineShoppe Opens its First Store in China's ChongQing.
Pall Life Science Sets up Proteomics Center at Bangalore.
Hong Kong and Guangdong Health Experts to Collaborate on Bird Flu Lab Testing.
Taiwan's Vita Genomics, Yang Ming University and India's IGIB Sign Agreement on Liver Disease Research.
Update on Bird flu.
Singapore Scientists Make Discoveries on Stomach Cancer.
US Imalux Corporation Inks Distribution Deals with Beijing Goodwell Company Limited.
Australia's CSL Expansion Facility and Vaccine Market.
India and the US Collaborate on Agriculture.
Korea's Professor Hwang's Fabrication of Embryonic Stem Cell Research.
Cygenics Awarded Another Patent.
Brisbane-based Alchemia Merge with Melbourne-based Meditech.
Imugene to Conduct Second Bird Flu Program.
LCT and The Bionic Ear Institute Collaborate on Research to Improve Hearing Loss.
Norwood Abbey takes MIT's Needle Licence.
Sinovac Biotech and LG Life Sciences Announce Distribution Agreement to Market Vaccines in China.
Novavax and Bharat Biotech to Co-develop Flu Vaccine.
Perth-based Proteomics Partners with New Delhi-based TechnoConcept.
Japan's Bioventures Today — A-Cube Inc.
SGS Opens Up New Contract Analytical Laboratory for Quality Control Testing in Singapore.
CyGenics Expands Into Europe.
Increasing US Investment Support for Starpharma.
Proteomics — An Australian-based Biotech Company.
Resonance Health to Expand US Business Operations.
Rockeby biomed Announces Four New Developments for Avian Influenza Test Kits.
Ranbaxy Buys Companies in Belgium, Italy and Romania.
Japan's Bioventures Today — HuBit Genomix Inc.
Abbott to Invest US$280 Million in the Largest Nutritional Plant in Singapore.
Covance Celebrates 10th Anniversary Milestone in Singapore.
NanoMaterials Technology Opens New S$2.5 Million Facility.
Waters Corporation Collaborates with Solectron.
Zentek Engineering Becomes First Irish Company to Set Up Asia Pacific HQ in Singapore.
Drug Discovery in China.
Pharmaceutical Industrial Partnering Trends in India.
CS Trail Closure Statement Unaffects VivaGel™ Clinical Trails Progress.
Living Cell Technologies to Run World's First Xenotransplantation Trial in Diabetes without Immunosuppression.
China Medical Technologies Inc—A Medical Device Company.
Sinovac Biotech to Increase Stake in China Subsidiary.
Aurigene Collaborates With Forest Labs.
Transgene Biotek Developing Oral Vaccine to Fight Diabetes.
ImClone and Bristol-Myers Team up for Cancer Treatment in Japan.
Japan Bioventures Today—Medical ProteoScope Co Ltd.
Fluidigm Launches Biomedical Product Development Center.
Singular ID Launches Enxure On-Line Portal with the Delivery of Two Enxure Evaluation Kits.
Exploring the Role of Glutathione in the Regulation of Immune Cell Function.
Does Oxidative Damage Cause Poor Healing?
Pathogenesis of Atopic Dermatitis in Singapore.
Proteomics and Colorectal Cancer Metastasis: Bird's-Eye View on Current Scenario and Our Contribution.
Zebrafish: A Small Fish Model for a Big Human Disease.
The Reign of a New Dictator: Circulating MicroRNA in Diabetes.
Engineering Artificial Vascularized Bone Grafts for the Repair of Large Bone Defects.
A 'Nano' Era for Blood Glucose Sensing.
Ancient Medicine with Newer Roles: Potential Role of Celastrol in the Treatment of Multiple Myeloma.
Proteins, Proteome and Proteomics.
A Novel Promising Biomarker and Therapy Target of Liver Cancer.
P&G Children's Safe Drinking Water Program Celebrates 10 Billion Litre Milestone in Singapore.
New In-Vitro Studies Reinforce Efficacy of BETADINE® Skin Cleanser against Viruses that Cause Hand Foot & Mouth Disease.
Singapore Ranked Fifth in its Readiness to Achieve a Fully Integrated Health System Reveals First Future Health Index.
SCIEX Announces High Throughput, Industrialised Omics Solutions.
Novartis Expands Partnership with Medicines for Malaria Venture to Develop Next-Generation Antimalarial Treatment.
ADVA Launches Dengue Mission Buzz Barometer Tool to Boost Critical Dengue Prevention Awareness and Preparedness Amongst ASEAN Community.
Innovative Diagnostics Awarded Unprecedented Westgard Sigma Certification in Singapore.
Global proteomics research is currently hampered by the extremely complexity of the proteome and the absence of techniques like the polymerase chain reaction in genomics which enables multiplication of a single protein molecule. Since all the existing analytical technologies cannot overcome the detection limit and the dynamic concentration barrier, development of improved analytical technologies at nanoscale, ideally those that could recognize single protein molecule in the presence of high abundant of others, is a high priority for proteomics. In this chapter, we will show the state-of-the-art of nanoproteomics, i.e., the application of nanotechnologies to proteomics. Various nanomaterials including carbon nanomaterials, magnetic nanoparticles, silica nanoparticles, polymer and copolymer nanoparticles, metal and metal oxide nanoparticles have been used to improve sensitivity, specificity, and repeatability of proteomic analysis especially when the multidimensional separation system coupled with MALDI-TOF-MS is used. Among them, gold nanoparticles (GNPs) and carbon nanotubes (CNTs) are the two most important nanomaterials: while GNPs are frequently utilized for enzyme immobilization, high throughput bioassay, selection of target-peptides and target-protein, CNTs including single-walled carbon nanotubes (SWCNTs) and mutiple-walled carbon nanotubes (MWCNTs) have wide applications to electronic sensor, sensitive immunodetection, nanobiocatalysis, affinity probes, MALDI matrices, protein digestion, peptides enrichment and analysis. In perspectives, a deep understanding of the structures and property of nanomaterials and interdisciplinary applications of nanotechnology to proteomics will certainly be revolutionary and intellectually rewarding.
Marinobacter hydrocarbonoclasticus was shown to have a high tolerance to copper sulphate. A minimum inhibitory concentration of 1.6 mM was determined, thus classifying Marinobacter hydrocarbonoclasticus as copper resistant. A proteomic approach based on two-dimensional gel electrophoresis provided a preliminary analysis over the differential protein expression induced by 1 mM of copper in Marinobacter hydrocarbonoclasticus. The copper stress led to a global change in the proteomic profile of the periplasmic fraction of this bacterium, involving modulation of the expression of 53 out of the close to 500 proteins detected, when compared with control growths with trace copper concentration.