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Let R be a ∗-ring with the center 𝒵(R) and ℕ be the set of nonnegative integers. In this paper, it is shown that if R contains a nontrivial self-adjoint idempotent which admits a generalized ∗-Lie higher derivable mapping Δ = {Gn}n∈ℕ associated with a ∗-Lie higher derivable mapping ℒ = {Ln}n∈ℕ, then for any X, Y in R and for each n in ℕ there exists an element ZX,Y (depending on X and Y) in the center 𝒵(R) such that Gn(X + Y ) = Gn(X) + Gn(Y) + ZX,Y.