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Tendons are frequently injured by direct trauma. Tendon adhesions are a common factor compromising the results of tendon repair and to this day represent one of the most challenging problems in hand surgery. Use of controlled motion splints during the early stages of tendon recovery increases tendon gliding. Thus, a variety of controlled motion splints have been developed. This paper introduces a new controlled motion splint called the Synergistic Wrist Motion Splint (SWIMS). The "seqential quadratic programming method" was used to optimize Yang's synertistic model of the wrist/hand system, with the results being embodied in a practical controlled motion splint. Derivation of the model is discussed in detail. The dimensions of a patient's hand are input into a general formula to generate a specific SWIMS configuration for the patient. Five prototype SWIMS splints were produced and tested on 5 normal subjects. A three-dimensional motion analysis system was employed to measure the relative motion between the wrist and finger joints due to passive muscle tension for the prototype SWIMS splints, and the results are compared with the mathematical simulation or model.