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The effective automatic location and tracking of a person's lip has been proven to be very difficult in the field of computer vision. A lip segmentation approach is proposed based on wavelet multi-scale edge detection across a lip map. The developed algorithm exploits the spatial interactions between neighboring pixels through wavelet multi-scale edge detection across the lip map. The algorithm produces better segmentation automatically without the need to determine an optimum threshold for each lip image. It has indicated the developed algorithm with superior performance by comparing with some existing lip segmentation algorithms.