In this paper, we give a characterization of homogeneous totally real minimal two-spheres in a complex hyperquadric Qn. Let f be a totally real minimal immersion from two-sphere in Qn, and τXY, τXc (see Sec. 2) are globally defined invariants relative to the first and second fundamental forms. We prove that if its Gauss curvature K and τXY are constants, and τXc vanishes identically, then f is congruent to F2k,2l constructed by the Boruvka spheres with n=2(k+l).