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The wrist and thumb postures adopted during the use of three different types of computer mouse (mini mouse; standard mouse; MouseMan) to perform eight standardized tasks were evaluated. Thirty elementary students between seven to twelve years of age were studied using a magnetic tracking system. The peak value and angular range of motion of the wrist and thumb extension/flexion and radial/ulnar deviation were measured during performing 8 standard tasks. There were statistically significant larger values in the standard mice with regard to extreme wrist extension. Angular range of wrist extension observed for the standard mice were also much higher than the mini mouse and MouseMan. There were statistically significant larger values in the MouseMan with regard to extreme wrist ulnar deviation, and an average decrease in extreme thumb flexion and angular range of thumb flexion. The results from the questionnaire showed that most elementary students preferred to use the standard mouse (40%) next was the MouseMan (37%); and the last the mini mouse (23%). The recommendation of mouse types based on the hand length for elementary students was not statistically significant in our study.