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SIMULATION OF A CLOSED LOOP MODEL EQUIVALENT ELECTRONIC OF NORMAL CARDIOVASCULAR SYSTEM AND VALVULAR AORTIC STENOSIS

Department of Technology, Faculty of Science and Technology, University of Djilali Bounaama, Thniet El Had street, Khemis Miliana, Ain Defla state, 44225, Algeria

E-mail Address: halaimi.amina@yahoo.fr

Corresponding author.

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BOUALEM CHETTI

Department of Technology, Faculty of Science and Technology, University of Djilali Bounaama, Thniet El Had street, Khemis Miliana, Ain Defla state, 44225, Algeria

E-mail Address: b.chetti@gmail.com

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BOUALEM LARIBI

Department of Technology, Faculty of Science and Technology, University of Djilali Bounaama, Thniet El Had street, Khemis Miliana, Ain Defla state, 44225, Algeria

E-mail Address: boulemlaribi@yahoo.com

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, and

OMAR LABBADLIA

http://orcid.org/0000-0003-1125-8755

Department of Technology, Faculty of Science and Technology, University of Djilali Bounaama, Thniet El Had street, Khemis Miliana, Ain Defla state, 44225, Algeria

E-mail Address: labba200@gmail.com

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https://doi.org/10.1142/S021951941950074XCited by:0 (Source: Crossref)

Abstract

This work presents a developed zero-dimensional cardiovascular (CV) system model, based on an electrical analogy, with a detailed compartmental description of the heart and the main vascular circulation which is able to simulate normal and diseased conditions of CV system, especially the stenosis valvular aortic. To know the effect of each parameter on hemodynamics, the number of parameters is increased by adding more segments. The developed model consists of 14 compartments. The results show that the severity of aortic stenosis (AS) effect varies with the effective orifice area and the mean pressure gradient for the case of no AS; the effective orifice area is 4cm² and the mean pressure gradient is 0mmHg, while for the case of mild AS, the effective orifice area is 1.5cm² and the mean pressure gradient is 27.24mmHg. For the case of moderate AS, the effective orifice area is 1.0cm² and the mean pressure gradient is 44.68mmHg. For the case of the severe AS, the effective orifice area is 0.61cm² and the mean pressure gradient is 77.51mmHg. It is found that the developed model can estimate an accurate value of the effective orifice area for any value of mean pressure gradient in AS. The results obtained for the CV system under normal and diseased conditions show a good agreement compared to published results.

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