Search
This Journal
This Journal
Anywhere
Quick Search in Journals
Enter words / phrases / DOI / ISBN / keywords / authors / etc
Access type:Only show content I have full access toOnly show Open Access
Advanced Search
0 My Cart
Sign in
Institutional Access

System Upgrade on Tue, May 28th, 2024 at 2am (EDT)

Existing users will be able to log into the site and access content. However, E-commerce and registration of new users may not be available for up to 12 hours.
For online purchase, please visit us again. Contact us at customercare@wspc.com for any enquiries.

ArticlesNo Access

Efficient synthesis and in vitro photodynamic anticancer study of new purpurinimide-hydrazone conjugates

PDT Research Institute, School of Nano System Engineering, Inje University, Gimhae 621-749, Korea

Search for more papers by this author

,

Department of Smart Foods and Drugs, Graduate School, Inje University, Gimhae 621-749, Korea

Search for more papers by this author

,

PDT Research Institute, School of Nano System Engineering, Inje University, Gimhae 621-749, Korea

Search for more papers by this author

,

PDT Research Institute, School of Nano System Engineering, Inje University, Gimhae 621-749, Korea

Search for more papers by this author

,

Science and Engineering College of Chemistry and Biology, Yantai University, Yantai 264005, China

Search for more papers by this author

, and

PDT Research Institute, School of Nano System Engineering, Inje University, Gimhae 621-749, Korea

Corresponding author, fax: +82 55-336-3872.

SPP full member in good standing.

Search for more papers by this author

https://doi.org/10.1142/S1088424611003239Cited by:9 (Source: Crossref)

Abstract

A series of new purpurinimide-hydrazone conjugates were synthesized, and their in vitro anticancer efficacy against A549 lung cancer cell lines was evaluated. It was found that the incorporation of the hydrazone group to the purpurinimide could increase their anticancer activities via a combination of photodynamic therapy and chemotherapy.

Keywords:

Most comprehensive & up-to-date research on PORPHYRINS
Handbook of Porphyrin Science now available in 46 volumes

References

T. J. Doughertyet al., J. Natl. Cancer. Inst. 90, 889 (1998). Web of Science, Google Scholar
E. S. Nyman and P. H. Hynninen, J. Photochem. Photobiol., B 73, 1 (2004). Web of Science, Google Scholar
B. C. Wilson and M. S. Patterson, Phys. Med. Biol. 53, R61 (2008), DOI: 10.1088/0031-9155/53/9/R01. Web of Science, Google Scholar
D. E. Dolmans, D. Fukumura and R. K. Jain, Nat. Rev. Cancer 3, 380 (2003), DOI: 10.1038/nrc1071. Web of Science, Google Scholar
R. K. Pandeyet al., Methods Mol. Biol. 635, 223 (2010), DOI: 10.1007/978-1-60761-697-9_16. Google Scholar
G. Zhenget al., J. Med. Chem. 44, 1540 (2001), DOI: 10.1021/jm0005510. Web of Science, Google Scholar
R. K. Pandeyet al., Photochem. Photobiol. 64, 194 (1996), DOI: 10.1111/j.1751-1097.1996.tb02442.x. Web of Science, Google Scholar
K. Kurohaneet al., Cancer Lett. 167, 49 (2001), DOI: 10.1016/S0304-3835(01)00475-X. Web of Science, Google Scholar
R. M. Tarantolaet al., Lasers Surg. Med. 40, 671 (2008), DOI: 10.1002/lsm.20720. Web of Science, Google Scholar
A. P. Castano, T. N. Demidova and M. R. Hamblin, Photodiagn. Photodyn. Ther. 1, 279 (2004). Web of Science, Google Scholar
G. Zhenget al., J. Org. Chem. 66, 8709 (2001), DOI: 10.1021/jo0105080. Web of Science, Google Scholar
M. F. Zuluaga and N. Lange, Curr. Med. Chem. 15, 1655 (2008), DOI: 10.2174/092986708784872401. Web of Science, Google Scholar
C. Lottneret al., J. Med. Chem. 45, 2064 (2002), DOI: 10.1021/jm0110688. Web of Science, Google Scholar
C. Lottneret al., J. Med. Chem. 45, 2079 (2002), DOI: 10.1021/jm0110690. Web of Science, Google Scholar
C. Lottneret al., Cancer Lett. 215, 167 (2004), DOI: 10.1016/j.canlet.2004.06.035. Web of Science, Google Scholar
C. Lottneret al., Cancer Lett. 203, 171 (2004), DOI: 10.1016/j.canlet.2003.09.001. Web of Science, Google Scholar
L. R. Morganet al., J. Med. Chem. 46, 4552 (2003), DOI: 10.1021/jm0301080. Web of Science, Google Scholar
J. Easmonet al., J. Med. Chem. 49, 6343 (2009), DOI: 10.1021/jm060232u. Web of Science, Google Scholar
V. Onniset al., Bioorg. Med. Chem. 17, 6158 (2009), DOI: 10.1016/j.bmc.2009.07.066. Web of Science, Google Scholar
G. Xuet al., Bioorg. Med. Chem. Lett. 18, 4615 (2008), DOI: 10.1016/j.bmcl.2008.07.020. Web of Science, Google Scholar
T. Horiuchiet al., Bioorg. Med. Chem. 17, 7850 (2009), DOI: 10.1016/j.bmc.2009.10.039. Web of Science, Google Scholar
M. Hayakawaet al., Bioorg. Med. Chem. 15, 403 (2007), DOI: 10.1016/j.bmc.2006.09.047. Web of Science, Google Scholar
J. Hofmannet al., Invest. New Drugs 27, 189 (2009), DOI: 10.1007/s10637-008-9156-x. Web of Science, Google Scholar
A. Andreaniet al., J. Med. Chem. 48, 3085 (2005), DOI: 10.1021/jm040888s. Web of Science, Google Scholar
K. M. Smith, D. A. Goff and D. J. Simpson, J. Am. Chem. Soc. 107, 4946 (1985), DOI: 10.1021/ja00303a021. Web of Science, Google Scholar
A. F. Mironovet al., Mendeleev Commun. 13, 156 (2003), DOI: 10.1070/MC2003v013n04ABEH001735. Web of Science, Google Scholar

Journal cover image

Vol. 15, No. 04

Metrics

Downloaded 81 times

History

Keywords