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Efficient synthesis and in vitro photodynamic anticancer study of new purpurinimide-hydrazone conjugates
Preview AbstractA series of new purpurinimide-hydrazone conjugates were synthesized, and their in vitro anticancer efficacy against A549 lung cancer cell lines was evaluated. It was found that the incorporation of the hydrazone group to the purpurinimide could increase their anticancer activities via a combination of photodynamic therapy and chemotherapy.