Genetics of Intracellular Traffic Jams: Multi-organellar Defects

The following sections are included:

• TRAFFIC JAMS IN EUKARYOTES

• INTRODUCTION TO HERMANSKY–PUDLAK SYNDROME (HPS)

  • Genetics

  • Incidence

  • Pathogenesis

  • Clinical Manifestation

  • Prognosis

  • Therapy

  • Diagnosis

• POSITIONAL CANDIDATE CLONING OF HPS GENES

• GENES REGULATING THE BIOGENESIS OF LROs

• ACKNOWLEDGMENTS

• REFERENCES