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Asymmetric zinc phthalocyanines substituted with a single carboxyl and triethyleneoxysulfonyl groups: synthesis, characterization and validation for photodynamic therapy

Duygu Aydın Tekdaş

Gebze Institute of Technology, Department of Chemistry, P.O. Box 141, Gebze, Kocaeli 41400, Turkey

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Ayşe G. Gürek

Gebze Institute of Technology, Department of Chemistry, P.O. Box 141, Gebze, Kocaeli 41400, Turkey

Corresponding author, tel: +90 262-605-3017, fax: +90 262-605-3005.

SPP full member in good standing.

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, and

Vefa Ahsen

Gebze Institute of Technology, Department of Chemistry, P.O. Box 141, Gebze, Kocaeli 41400, Turkey

SPP full member in good standing.

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https://doi.org/10.1142/S1088424614500709Cited by:11 (Source: Crossref)

Abstract

This work describes modular pathway towards the synthesis of new specific unsymmetrically (AB3) zinc phthalocyanines that contains three polyoxy ethylene and monocarboxylic acid groups as photosensitizers. Their photophysical and photochemical properties are studied. General trends are described for quantum yields of fluorescence, photodegradation and singlet oxygen quantum yields of these compounds. Therefore, these novel phthalocyanines could potentially be good photosensitizers for photodynamic therapy.

Dedicated to Professor Nagao Kobayashi on the occasion of his 65th birthday

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