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Three-dimensional (3D) photocatalytic devices are economical and environmental, since they can be easily recycled and reused. In this paper, a kind of 3D photocatalytic device with a rod diameter of 250 μm was fabricated using the aqueous-based α-Fe₂O₃ ceramic inks by direct ink writing (DIW) method. The properties of the DIW woodpile samples were investigated by X-ray diffraction (XRD), scanning electron microscope (SEM) and optical microscope. The result shows that the ink with solid content of 71.4 wt.% exhibits a shear thinning behavior and proper viscoelastic properties, which ensure a feasible extrusion in the whole shaping process. The sample sintered at 800°C in air causes photocatalytic degradation of methylene blue (MB) solution under the ultraviolet (UV) light. The photocatalytic properties of the α-Fe₂O₃ woodpile structure was characterized by the UV-visible light spectrophotometer, and it was found to be better than that of bulk sample with same weight for its higher specific surface. The DIW technique would offer a potential method for the design and fabrication of 3D photocatalytic devices.

Migraine is a re-occurring type of headache and causes moderate-to-severe pain that is troubling or pulsing. The pain occurs in half of the head, and common symptoms are photophobia, phonophobia, nausea, depression, anxiety, vomiting, etc. This study evaluates the prevalence of migraine and responsible genes through molecular modeling in the region of Bahawalpur, Pakistan. This research was aimed to determine the prevalence of migraine-causing genes in the population of Bahawalpur and also to do molecular and in-silico analysis of migraine-causing gene as no similar research was conducted before. The disease was characterized and diagnosed under the criteria of the Second Edition of the International Classification of Headache Disorders and molecular identification of migraine-causing genes, i.e. GRIA1, GRIA3, and ESR1, by PCR amplification. The total number of samples collected for migraine patients was 230, out of which 30 were positive for PCR amplification of the genes GRIA1, GRIA3, and ESR1. Therapeutic potentials of commercial drugs, namely Cyclobenzaprine, Divalproex, Ergotamine, and Sumatriptan, were analyzed in silico through molecular docking. Ergotamine demonstrated the highest binding affinity of $-$8.4 kcal/mol for the target molecule and, hence, the highest potential. The bivariate analysis showed that the prevalence of migraine concerning gender and age was significantly correlated ($\alpha =0.01$, $p=0.212$). It was observed that almost 31.4% of women suffered from headaches daily, 70% weekly, 28.1% monthly, and 23.5% rarely. Comparatively, only 8.3% of males suffered from daily headaches, 34% weekly, 12.8% monthly, and 14.9% rarely. The study shows promising results and encourages future researchers to conduct such a comprehensive epidemiological study on an even larger population to justify a more precise association of risk factors involved in migraine pathophysiology.