We have compared the binding energy of nuclear matter and the nucleon–nucleus optical potential, calculated in Brueckner theory starting from both the soft-core Urbana V-14 and the hard-core Hamada–Johnston internucleon potentials. Our results show that the real central part of the optical potential calculated from V-14 is about 10 MeV deeper than from the hard-core potential in the energy region 1–200 MeV. This greater depth mainly comes from the internucleon S- and D-states. In these states, the V-14 and Hamada–Johnston potentials give different phase shifts, the V-14 being in better agreement with experimental data. This difference is further enhanced by the Pauli principle in the calculation of the optical potential. Our analysis of proton–40Ca differential cross-section and polarization data, in the energy region 30–200 MeV, shows that the optical potential calculated using V-14 is in better agreement with the data as compared with the Hamada–Johnston potential.