In the spirit of Bar-Natan’s construction of Khovanov homology, we give a categorification of the Vandermonde determinant. Given a sequence of positive integers →x=(x1,…,xn), we construct a complex of colored smoothings of the two-strand torus link T2,n in the shape of the Bruhat order on Sn, and apply a topological quantum field theory (TQFT) to obtain a chain complex whose Euler characteristic is equal to the Vandermonde determinant evaluated at →x. A generalization to arbitrary link diagrams is given, yielding categorifications of certain generalized Vandermonde determinants.