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To improve the predictive ability of computational fluid dynamics (CFD) on the transonic buffet phenomenon, NASA SC(2)-0714 supercritical airfoil is numerically investigated by noninstructive probabilistic collocation method for uncertainty quantification. Distributions of uncertain parameters are established according to the NASA wind tunnel report. The effects of the uncertainties on lift, drag, mean pressure and root-mean square pressure are discussed. To represent the stochastic solution, the mean and standard deviation of variation of flow quantities such as lift and drag coefficients are computed. Furthermore, mean pressure distribution and root-mean square pressure distribution from the upper surface are displayed with uncertainty bounds containing 95% of all possible values. It is shown that the most sensitive part of flow to uncertain parameters is near the shock wave motion region. Comparing uncertainty bounds with experimental data, numerical results are reliable to predict the reduced frequency and mean pressure distribution. However, for root-mean square pressure distribution, numerical results are higher than the experimental data in the trailing edge region.