Narrow Results

Trace elements play important roles in cells. Nuclear techniques as traditional PIXE, SPM and SR-XRM provide solid tools for quantitative element analysis. The article presents element-distribution maps of endometrium, nerve cell and relative quantity tables. Advantages of PIXE, SPM and SR-XRM techniques, especially in application to cell biology, are discussed. PIXE has a large beam and is convenient in measuring a large quantity of samples. SPM gives element-distribution maps owing to its high resolution. SR-XRM tells quantity of elements by its good sensitivity and nondestructive irradiation. The combination of PIXE, SPM and SR-XRM demonstrates that Zn is a component of cell membrane and is proved to be a complementary way which will open vast vistas for cell analysis.

Probing Cell Death on A Foreign Land.

Australian Listed biotech firms to Benefit from New Alliance.

CyGenics Signs Collaboration Agreement with the Blood Center of Zhejiang Province.

Shanghai Genomics.

CMIC and Accium Collaborate to Provide Exploratory-IND and Low-Radiation PK/ADME Service.

Stelic Discovers New Treatment Method for Acute Liver Failure.

Japan Bioventures Today — Regimmune Corporation.

Inventory Response by Baxter on its Preliminary Findings for Bird Flu Vaccine.

Davos Life Science Opens World's Largest R&D Center on Tocotrienols in Singapore.

Invitrogen Opens First of its Kind Supply Center in Singapore.

A window into Randy Schekman’s life.

For the month of August 2020, APBN explores the wonders of the human brain and how researchers and scientists are leveraging on technological advancements to gain insights to its inner mechanisms. In the Columns section, scientists from ACT Genomics discuss the topic of Precision Oncology and patient selection for PARP inhibitor treatment in BRCA- & HRR-associated cancers. This month APBN interviewed Dr Ling Kai Yi, co-founder and Chief Science/Technology Officer of Singapore-based clean meat company, ShiokMeats to take a closer look at how the team is fighting for sustainability in the seafood industry.

The migration of immature neurons from proliferation zones to their place of final differentiation occurs in many areas throughout the developing vertebrate central nervous system. As migration represents a key step in neuronal differentiation it has been modeled extensively in cell culture, matrix gels or explanted tissues. Due to the many complex interactions that are involved in this dynamic process, it would be ideal though to observe neuronal migration non-invasively directly in the developing organism. Furthermore, not only migratory pathways have to be characterized in detail, but also the underlying cell biology of neuronal migration needs to be revealed. For example, addressing how signal transduction is mediated into directed cellular movement at the level of different cellular organelles is not only crucial for understanding the cellular and molecular interplay of dynamic brain differentiation but also for revealing the etiology of neuronal migration diseases. Recent advances in zebrafish conditional genetics and simultaneous multi-cistron expression combined with the progress in high-resolution high-speed bio-optics promise that neuronal migration can be resolved at unprecedented detail in this organism. Thus the stage is set in zebrafish for true in vivo cell biology, which will allow for the re-addressing of the many models of neuronal migration derived from in vitro data of cultured cells or tissue explants. Hence zebrafish can serve to fuse the large fields of developmental genetics and cell biology in vertebrates.