Narrow Results

Progen’s Cancer Drug Trial Progresses.

EpiTan to Expand into Dermatology Products.

Progen Adds Drug to Development Pipeline.

Cellestis Produces New TB Test.

Chinese University to Produce Medical Cyclotrons with GE.

China National Genome Center and Genetastix Start Joint Venture.

Dr. Morepen Distributes Products in Bangladesh.

Ranbaxy Hits OTC Market.

USV to Produce Biotech Medicine for Foot Ulcers.

Shionogi Launches Anti-allergic Product.

Takara Bio Develops Glass Slide for DNA Microarray.

Takeda and Biosense Collaborate to Distribute ELISA Kits.

NEC Offers High-throughput Turnkey System for Homology Searches.

SC BioSciences Establishes Business Partnership with Proteom.

GenoProt Co.

MGenbio.

Fonterra Puts NZ$60 Million into Biotech Venture.

Tru-Test Acquires Brainz Instruments from Neuronz.

Inhibitex in Research Collaboration with Singapore’s BMTC.

TaiGen in Collaboration with Italy’s BioXell.

TurboWorx Revolutionizes Asian Life Science Computing.

Asia's Medical Technology Start-ups Get New Fast Track to Market via Partnership between Cambridge Consultants and Clearbridge Accelerator

Mitsubishi Electric and Sembcorp Industries to Testbed Novel Ozone Backwashing Energy-Saving Membrane Bioreactor

LEO Pharma Enters Biologics through Strategic Partnership with AstraZeneca

Bayer and X-Chem Expand Drug Discovery Collaboration to Discover Novel Medicines

New Gas Chromatography System Brings Power of Orbitrap GC-MS Technology to Routine Applications

A*STAR and MSD Establish a New Research Collaboration to Advance Peptide Therapeutics

Stem Cells Engineered to Grow Cartilage, Fight Inflammation

JAPAN – Asia Pacific Medical Technology Association (APACMed) announces partnership with Japan Federation of Medical Devices Associations (JFMDA).

UNITED STATES – Gene Mutation May Speed Up Memory Loss in Alzheimer’s Disease.

UNITED STATES – Know the Facts About Skin Cancer.

UNITED STATES – Another Reason to Exercise: Burning Bone Fat – a Key to Better Bone Health.

AUSTRALIA & NEW ZEALAND – LCT Collaborates with Auckland University Centre for Brain Research to Extend Product Pipeline.

TAIWAN – Peptide Nasal Spray to Delay Onset of Alzheimer’s disease.

TAIWAN – TLC178 Designated by US FDA as Drug for Rare Pediatric Disease in the Treatment of Rhabdomyosarcoma.

Asia-Pacific, the rising region for cancer vaccine clinical trials.

Non-small cell lung cancer has largest number of clinical trials in Australia.

Global dermatology pipeline to see shift towards increased usage of biologics.

FDA approves first 0.1 mg auto-injector for life-threatening allergic reactions in infants and small children.

FDA approves first two-drug regimen for certain patients with HIV.

New early-breast cancer drug to be made available in Australia, New Zealand and South-East Asia.

Multi-omic data analytics collaboration between the University of Oxford and Holmusk.

NRGene’s genomic analysis project with Monsanto advances.

Samsung BioLogics receives first FDA approval at world’s largest plant.

TLC welcomes Mayor of Leiden and delegation to Taipei headquarter.

Warren Wang appointed senior vice president and president of Asia Pacific of Boston Scientific.

MiRXES reveals globalisation plans for 2018 and 2019.

QuintilesIMS is now IQVIA.

Quotient Sciences launches as the new global identity for Quotient Clinical.

ESMO Asia 2017 Congress.

More care is needed for cancer supportive care.

ALEX study shows alectinib 600 mg more effective than crizotinib in Asian lung cancer patients.

Study analyses mutations in cerebrospinal fluid in lung cancer with brain metastases.

Study finds all Myanmar mouth cancer patients chew betel quid.

The following topics are under this section:

• Tencent makes medical information readily available to the public
• United States FDA approves first China-made cancer drug
• Chinese conglomerate breaks ground to create network of international hospitals in China in strategic cooperation agreement
• China launches project on lung cancer gene atlas
• Dermatology centre in Shanghai to pursue research in biologicals
• Inner Mongolia ends medical observation in pneumonic plague case
• China looks to expand malaria aid in Africa

Nanotoxicology is a concern. While skin exposure is generally perceived as less hazardous than inhalation or ingestion of engineered nanoparticles, there remain significant knowledge gaps in the topic to suggest greater caution in making a conclusion. Penetration of nanoparticles across an intact skin barrier is low. However, the verdict is still out on how this will change in situations where the skin barrier is compromised. Many studies on the interaction of nanoparticles with biological systems including skin cells have been reported. Under different scenarios, nanoparticles commonly found in topical skin products have been shown to be capable of exerting a variety of toxicological influences. These influences include causing cell death, stress, inflammation and damage to DNA. While alarming, it should also be noted that there remains much confusion and contradiction in the literature due to the complexity of studying cell–nanoparticle interactions. This review aims to provide a concise perspective on our current understanding of nanotoxicology in the skin, and identify the knowledge gaps where research efforts may be focused to help clarify the uncertainties in the field.