Narrow Results

The aim of this review is to critically examine the clinical trial research on Traditional Chinese Medicine (TCM) as an intervention in treating heroin addiction in People's Republic of China. This review examines Chinese-language-only publications for the patent medicines: Shenfu Tuodu, Fukang Pian, and Shifu Sheng. Other compound medicines will be reviewed in future publications.

A systematic review of the literature was conducted in Western and Chinese databases. Most trials were excluded because they did not declare randomization and had poor methodology or reporting. The majority of clinical evidence in the random controlled trials demonstrates good evidence for TCM patent medicines in heroin addiction treatment. When compared to typical Western medications, TCMs demonstrate fewer side-effects, in addition to equal measures of treatment efficacy and safety.

Compared with monotherapy, combination therapy is the first choice and the most promising method for the treatment of many complex diseases. Due to the wide variety of drugs, it is often difficult to choose desirable combination drugs with synergy and low risk. Additional research should always be done before combining drugs because the combinatorial effects can be synergistic, additive, or even antagonistic. Synergistic drugs work together to cause an effect greater than the sum of its parts. Some studies propose different approaches to detect synergism between two or more drugs. Based on the framework of bifurcation-based method, we propose an approach to screen another potential synergistic drug for a given drug. Different from other methods, the approach can help us screen and detect drugs which have a synergistic effect with a known drug, thus playing critical roles in combination therapy. In order to demonstrate the effectiveness of the approach, we apply it to three models, i.e. the zeroth-order reaction model, the galactose model, and the epithelial-to-mesenchymal transition network. The approach provides a theoretical basis for rational design of combination drugs and new use of old drugs.

New Entry to Australian Stock Exchange: Acrux.

Peplin's Phase I Clinical Trial Completed.

Prima BioMed & AstraZeneca in Licensing Agreement.

Ultratech India Restrained from Tampering with Pfizer's Viagra Trademarks.

India Offers Competitive New Drug Solutions.

Rofecoxib Formulation Discontinued after Health Ministry's Ban.

GSK Focuses on In-licensing for Other Global Companies in India.

Forthcoming Pharmaceutical Hub in Bengal.

Upcoming Medical Industry Zone in Japan.

Roche and Japan Tobacco in Licensing Collaboration for Potential Dyslipidemia Therapy.

Tapping on Nature for Drugs.

The article starts of with an overview of the Institute of Bioengineering and Nanotechnology. It describes the focus of the institution. There are two research articles after the summary. One of it touches on non-cytotoxic and photostable quantum dots for bioimaing applications and the other is on silica-coated nanocomposites of magnetic nanoparticles and quantum dots.

The article gives an insight into the background and products of Choongwae Pharma Corporation.

AUSTRALIA – Australia Developing Breakthrough Leukemia Research Strategy.

AUSTRALIA – Obesity Associated With Detrimental Changes in Ovary.

AUSTRALIA – Queensland's Dengue Outbreak Worsens.

CHINA – Global Fund Assists Guangxi In Anti-AIDS Programs.

CHINA – Chinese Scientists Clone 5 Human Embryos for Research.

CHINA – China Stockpiles Vaccine for Possible Bird Flu Outbreak.

CHINA – QIAGEN Supports Cervical Cancer Screening for Underprivileged.

CHINA – JCI and Peking University Collaborate on Patient Safety and Education in China.

CHINA – Scientists Identify Key Drug Target in Bird Flu Virus.

CHINA – China Facing Burden from Chronic Diseases.

CHINA – Chinese Scientists Discover Achilles' Heel for SARS Virus.

CHINA – 18 HFMD Child Fatalities in China.

CHINA – Mainland China Reports 838 Infectious Disease Fatalities in February.

HONG KONG – Lethal Fungal Contamination in Drug.

HONG KONG – Hong Kong Experiences Record High HIV Infection Level.

INDIA – Stem Cells Help Save Man's Leg From Amputation.

INDIA – Human Trials for Kalaazar Vaccine Soon.

INDIA – Stem Cell Banks Expand on Prospects of Healthy Dividend.

INDIA – Biotech Rice to be Commercially Available in India by 2012.

INDIA – Rising Demand for Herbal Medicines in Jammu Kashmir.

INDIA – India, UNESCO to Set up Biotech Centre.

INDONESIA – Health Ministry Clears up Vaccine Dispute.

JAPAN – Bird Flu Detected in Second Quail Farm in Central Japan.

NEW ZEALAND – NZ Med Tech Sector Continues to Thrive.

NEW ZEALAND – Aerobics Classes can Cause Hearing Damage.

SINGAPORE – Dengue fever is on the rise in Singapore.

SINGAPORE – Will New US Policy Stem Talent Flow to Singapore?

SINGAPORE – HBOT Now Available at SGH.

SINGAPORE – Cancer Society's Colorectal Screenings Helped Save 123 lives.

SINGAPORE – National Heart Centre Singapore Unveils New Techniques for Heart Patients.

SINGAPORE – NTU Seals Global Partnerships in Environmental Sciences R&D.

SINGAPORE – NUH Cancer Center in Major Cancer Drug Trial.

SINGAPORE – Need More Trained Doctors? Build New Medical School.

VIETNAM – Harmful Bacteria Found in Bottled Water.

OTHER REGIONS — EUROPE – Hot Tea Linked to Throat Cancer.

USA – New Vaccine Method 'Offers Instant Immunity'.

AUSTRALIA – Minimizing Spread of Deadly Hendra Virus.

AUSTRALIA – Breakthrough High Blood Pressure Treatment Trial Down Under.

AUSTRALIA – Australia Sees Rise in Newborn Withdrawal Syndrome.

CHINA – CAS, Hong Kong University Set Up Joint Lab of Natural Medicine.

CHINA – Chinese Researchers Discover 20 Essential Genes in Polyoxin.

CHINA – China Aims to Lead Asia's Stem Cell R&D.

CHINA – China Rural Areas on High Alert for Hand, Foot and Mouth Disease.

CHINA – Hepatitis Infects 64 at China Hospital.

CHINA – China's Colorectal Cancer Drug Market will More Than Double by 2012.

CHINA – Critical Gene for Enhancing China's Super Rice Yield Identified.

CHINA – Chinese Scientists say New Discovery May Yield Clue to Cure Human Infertility.

HONG KONG – Compound to Fight Bird Flu Identified.

INDIA – Yashoda Cancer Institute Treats First Patient In India Using RapidArc Radiotherapy Technology.

INDIA – Indian Pharma Industry May Gain $18.4 bn from Global Market.

INDIA – Philips to Make India Hub for Medical Equipment Manufacturing.

JAPAN – Herbal Medicines to Treat Gastrointestinal Disease.

SINGAPORE – Tetravalent Dengue Vaccine Trial in Singapore.

SINGAPORE – Minimally Invasive Robot-Assisted Surgeries for Heart Patients.

SINGAPORE – US-Based Company Launches Singapore Doctor Search Site for Medical Travelers.

SINGAPORE – Genetic Research: Time for a rethink?

SINGAPORE – Test Kits to be Licensed.

SINGAPORE – Local Team Develops Method to Predict Heart Disease.

SINGAPORE – Consumer Genetic Tests – A Cause for Worry?

SINGAPORE – S'pore Firm's Test Kit Joins the Fight.

SINGAPORE – Singapore Gives New Hope To The Blind.

SINGAPORE – Singapore and Korea Research Institutes Embark on Landmark Collaboration for Breakthroughs in Micro and Nanotechnology.

SOUTH KOREA – Institute Develops Cheap Cholera Vaccine.

TAIWAN – Herbal Substance Developed for Cardiovascular Disease.

TAIWAN – Prototype of Household Breast Cancer Detector Unveiled.

TAIWAN – Breakthrough in New Diabetes Drug.

New President Elected to Helm ABLE.

DIA appoints Chair of Regional Advisory Council, Japan.

New Leadership Appointments of A*STAR to Drive Research Innovation.

Interview with Frost & Sullivan — Celebrating Best Practices in Healthcare.

Interview with InterSystems Corporation — Connecting Applications, Processes and People Intelligently.

Interview with Philips Healthcare — Excellence in Medical Imaging & Radiology.

Interview with Roche Diagnostics — Cutting-Edge Clinical Diagnostics.

Australian Scientists Make Breakthrough Understanding in Breast Cancer.

New Functional Protein Discovered for Liver Immunology.

Important New Links Found for H. Pylori – the Cancer-causing Bacterium.

AUSTRALIA – Hospital Infections Bring Costly Loss in Lost Bed Days.

CHINA – Novel Mechanism in Chinese Herbs Discovered for Cancer Treatment.

CHINA – "Dung of the Devil" Plant Roots Point to New Swine Flu Drugs.

CHINA – New Center at Chinese Academy of Sciences Pushes Life Science Innovation.

CHINA – A New Function of Insulin Receptor Discovered.

JAPAN – Researchers Identify Fat-Causing Protein.

SINGAPORE – Operation Conducted Entirely Through the Navel.

SINGAPORE – Saliva From Blood-Feeding Bug Could Help Prevent Heart Attacks.

SINGAPORE – 17 Projects Awarded Grants by A*STAR.

SINGAPORE – Third Medical School for Singapore.

SINGAPORE – Singapore's Medical Technology Sector Reports Strong Growth.

SINGAPORE – Scientists Unlock Secret to Youthful Skin.

SINGAPORE – Singapore Gears Up for Influenza A (H1N1) Vaccines.

SINGAPORE – NUS Gets World's Most High-Tech Microscope.

SINGAPORE – Waseda University Opens First Overseas Biosciences Research Institute in Singapore.

TAIWAN – Taiwan Makes Headway in New Drug Development.

TAIWAN – Nutrition Sensor in Plants Pivotal in Understanding Molecular Equilibrium in Human Body.

VIETNAM – U.S. Provides Aid to Vietnam for Pandemic Preparedness.

EUROPE – Heart Risks Cut Life Span by 10 Years.

NORTH AMERICA – Bad Drug Effects in Children from Medicines.

NORTH AMERICA – Virus Linked to Prostate Cancer Discovered.

NORTH AMERICA – Will H1N1 Mutate into "Superbug"?

Australian Company Develops Potential UV Vaccine.

Phylogica Enters Agreement with Roche to Evaluate Phylomer Technology.

CSL Behring Awards $87,000 to Patient Organizations in USA.

Pfizer, Crown Bioscience Tie up for Asian Cancers R&D.

Sinovac Files Clinical Trial Application with SFDA for Vaccine against Hand, Foot, and Mouth Disease.

Takeda and Pfizer to Co-Promote Takeda's Actos^® (pioglitazone HCl) for the Treatment of Type 2 Diabetes in China.

Alvogen Launches Asia Operations.

Praj to Collaborate with Novozymes on Advanced Biofuels.

Biocon and HCG Group of Hospitals Join Hands to Fight Against Cervical Cancer.

Shantha Introduces India's First Oral Cholera Vaccine.

Pfizer, TCGLS to Develop Preclinical Candidate Molecules.

Hospira to Acquire Orchid's Generic Injectable Pharmaceuticals Business.

Dicerna Pharma, Kyowa Hakko to Collaborate on RNAi.

Ambit Biosciences and Astellas Enter Strategic Partnership.

Inno Biologics, CEVEC for Using Sign Agreement Human CAP Technology.

Patrys to Work with CSL to Explore Antibody Drugs.

Starpharma and Lilly Sign New Drug Delivery Collaboration for Human Pharmaceuticals.

Sanofi, Minsheng in China Consumer Health Venture.

Biocon Signs MoU with Malaysia's BiotechCorp.

Biocon, Bayer Tie up to Fight Diabetes in India.

Ranbaxy to Acquire Bangalore Based Biovel Life Sciences.

DiscoveRx, Jubilant Biosys Announce Agreement for Screening Services.

BD Biosciences Collaborates with ReaMetrix to Develop New, Affordable CD4 Testing Products to Help Fight HIV/AIDS in Developing Countries.

Aegis Therapeutics and Dr. Reddy's Announce Strategic Alliance.

Penwest Enters Into Research and Development Agreement with Otsuka Pharmaceutical.

AstraZeneca and CrystalGenomics Form Research Collaboration to Develop Novel Anti-Infective Treatments.

International and Local Recognition for Singaporean Biotech Start-up – Curiox Biosystems.

Roche Establishes New Medical Research Hub in Singapore.

Virbac Unveils First Regional R&D Center in Asia.

Open Innovation: Next Frontier In Global Biopharma Industry.

Benitec Limited Granted Hepatitis C RNA Interference Patent in US.

HUYA Bioscience International and China Medical City Forge Alliance.

Chindex, Fosun Pharma Form Joint Venture.

Daiichi Sankyo and Ranbaxy to Integrate New Drug Research and Development System.

TAKE Solutions and Reliance Life Sciences Enter Strategic Alliance.

Veeda Oncology Announces $8.4 million in New Business.

Medicago signs Vaccine MOU with PT Bio Farma.

Kyowa Hakko Kirin to Enter Out-licensing Agreement with Biovail.

Sosei to Acquire Activus Pharma.

Takeda to Expand Operations in South Korea.

SymBio and Cephalon Sign License Agreement.

Quintiles Announces Clinical Research Partnership with the University Malaya Medical Centre.

Roche's New DNA Sequencer Opens Innovation in Genomic Research.

Dow Microbial Control Academy Showcases Industrial Leadership and Expertise.

AUSTRALIA – Australian Drug Delivery System to Kill Cancer.

AUSTRALIA – Vitamin C Helps Fight Cancer.

AUSTRALIA – Keyhole Hysterectomy Surgery Best.

AUSTRALIA – UQ and Alere Team to Develop Dengue Fever Test.

AUSTRALIA – World's Largest ADHD Study at UQ.

CHINA – Book on Chinese Patent Medicines Soon.

CHINA – China's Organ Donations on the Rise.

CHINA – Toxic Cancer-Causing Dyes Found in China Garments.

INDIA – Stereotactic Lung Radiosurgery Treatment First in India.

JAPAN – Japan Contributes $10 Million to AIDS Vaccine Development.

KOREA – UMass, Korea Explore Asian Medicinal Herbs for Diabetes.

KOREA – South Korea Industries to Invest $18.5 Billion in Clean Energy Projects.

MALAYSIA – Future Chinese Medicine Centre in Salak Tinggi.

NEW ZEALAND – Vegetable Growers Using Banned Chemical.

SINGAPORE – GIS Partners Life Technologies to Develop New DNA Sequencing Protocols.

SINGAPORE – HPB's Be Positive!

SINGAPORE – A*STAR's ICES Receives GSK-Singapore Partnership for Green & Sustainable Manufacturing Grant Award.

SINGAPORE – New Drug for Eye Disease.

SINGAPORE – Singapore to Make Smallest Biosensors in the World.

SINGAPORE – IME and Stanford University to Develop Nano Circuits Inspired by Human Brain.

TAIWAN – Scientists Reach Hybrid Sterility Breakthrough.

TAIWAN – Cooperation Agreement Between Taiwan and Malaysia Med-tech Firms Signed at BioBusiness Asia.

OTHER REGIONS — NORTH AMERICA – Researchers Discover Most Powerful HIV Antibody.

CHINA: Medical Tourism's Dark Horse?

Treating Chronic Low Back Pain with Accupuncture.

Arsenic Nanoparticle Blocks Aggressive Breast Cancer.

Interactions Between Herbs and Drugs.

CSL to Set up Biotech Facility in Victoria.

Merck to Work with Sinopharm to Market HPV Shot and Other Vaccines in China.

China PharmaHub Corp. Signs Merger Agreement with World Wide Relics.

Lambda Therapeutic Research Acquires North American CRO.

Cochlear Commences Operations in India.

CordLife Introduces Quality Guarantee Program in India.

Opto Circuits Acquires US-based Unetixs Vascular.

Stem Cell-Based Treatment Collaboration for Corneal Vision Impairment, International Stem Cell Corporation.

Axiogenesis In-Licenses Yamanaka Patent Portfolio from iPS Academia Japan.

ArQule, Daiichi Sankyo to Conduct trials for NSCLC Drug.

Pfizer, Samsung Medical Center to Study Liver Cancer.

Agilent Technologies Signs Agreement with Government of Malaysia to Cooperate in Biotechnology.

Bayer Animal Health, Paraco Agree on Access to Lead Molecules.

A*STAR & Cytos Biotechnology Collaborate on Influenza Vaccine.

Phylogica to Pursue Antimicrobial Peptide Discovery with MedImmune.

Novel Stem Cell Therapy can Help Diabetic Children Live Normal Lives.

3SBio and Isotechnika Sign Partnership to Develop Voclosporin in China.

China PharmaHub Signs Agreement with Chengdu Yongkon Pharmacy.

Thermo Fisher Scientific Opens Technology Center in Shanghai.

Strand and Narayana Hrudalaya Collaborate in Translational Cancer Research.

Lohmann Animal Health and Suguna Create a Poultry Vaccine JV.

Dr Reddys Launches World's First Generic Darbepoetin Alfa.

Oridion Signs Deal with IMI for Japanese Market.

Astellas and UMN Pharma Sign Vaccines Pact.

Pathway Therapeutics Closes $4.5 Million Financing for Novel PI3K Inhibitor Portfolio.

Emergent BioSolutions and Temasek Life Sciences Ventures Establish JV to Develop Broad Spectrum Pandemic Flu Vaccine and Therapeutic.

AUSTRALIA – Australian Scientists Make Breakthrough on HIV's Infectious Grip.

AUSTRALIA – Australian Researchers Developing New Dengue Vaccine.

AUSTRALIA – Heart Attack Genes Discovered.

AUSTRALIA – Australian Researchers Find Blindness Genes.

AUSTRALIA – Innovative Spinal Surgery Performed at Austin Health.

AUSTRALIA – Future Risks for Child Cancer Survivors Seven Times Higher.

AUSTRALIA – Triggers Found on Asthma Risk.

AUSTRALIA – One-dose Malaria Killer Drug.

BANGLADESH – 589 People Confirmed to be infected by Anthrax in Bangladesh.

CHINA – Banned Chemical Found in China Cosmetics.

CHINA – China PharmaHub Corp. Introduces A 'Magic Bullet' Liver Cancer Therapy.

INDIA – BARC Develops Radionuclides for Inoperable Cancers, Arthritis.

INDIA – Vaccine Makers to Lobby for Higher Immunization Coverage.

SINGAPORE – Singapore and Seattle Eye Banks Collaborate to Increase World Supply of Tissue for Sight-Restoring Corneal Transplants.

SINGAPORE – Doctors Discover Tamiflu-Resistant H1N1 Superbug.

SINGAPORE – P&G Partners A*STAR to Strengthen R&D Presence in Singapore.

SINGAPORE – NCCS-led Study Helps Doctors to Better Identify Treatment for Colorectal Cancer Patients.

OTHER REGIONS — EUROPE – Gene Therapy Success for Anemia Patient.

OTHER REGIONS — NORTH AMERICA – Researchers Find Genes Linked to Ovarian Cancer.