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  • articleNo Access

    PIXE ANALYSIS OF PEANUTS PLANTED IN JAPAN AND IMPORTED FROM ABROAD

    Elemental concentrations in Chinese peanuts have been analyzed and compared with those in Japanese peanuts by means of a PIXE (Particle Induced X-ray Emission) technique with an internal standard method to investigate traces of residual agricultural chemicals or toxic elements in them because frequent detection of excessive agrochemical residues in food imported from China has posed serious health concerns to Japanese people. We prepared the samples by separating the peanut seed into two cotyledons (seed leaves) and an embryo. Significant differences in elemental concentrations between Chinese and Japanese peanuts have not been observed as far as the peanut seeds used in the present measurement are concerned. The concentrations of the several elements in the embryo are higher than those in the cotyledon.

  • articleNo Access

    Bioboard

      AUSTRALIA – New Leukemia Discovery.

      AUSTRALIA – Scientists Identify Proteins to Fight Malaria.

      AUSTRALIA – Organ Donation Rates up in NSW.

      AUSTRALIA – Chlamydia Rates have Hit an All-time High in Australia, with Reports of Infections Tripling Over the Past Decade.

      CHINA – Chinese Scientists Caught Faking Research Papers.

      CHINA – New Findings for Cancer Treatment.

      CHINA – A/H1N1 Flu to Keep Spreading in China.

      CHINA – Scientists Discover Avian Influenza Outbreak Closely Related to Bird Migration.

      CHINA – Vitamin C Boosts the Reprogramming of Adult Cells into Stem Cells.

      CHINA – Georgia State Partners with Institutions in China and Taiwan.

      CHINA – China a Rising Star in Regenerative Medicine Despite World Skepticism of Stem Cell Therapies.

      HONG KONG – Hong Kong Discovers Pigs with H1N1 Virus.

      HONG KONG – Two more Norwegian-like Mutations of Human Swine Influenza Virus Detected.

      INDIA – India, Sweden to Boost Bilateral Ties in Healthcare.

      INDIA – Agri-Biotech Focus at Bangalore India Bio.

      PHILIPPINES – Biologist Finds New Vaccine for Malaria in Philippines.

      SINGAPORE – EADS and A*STAR's ICES to Collaborate on Biofuels.

      SINGAPORE – Singapore, France Collaborate to Further Scientific R&D.

      SINGAPORE – Rare Neurological Complications of Cancer Successfully Treated by NCCS.

      SINGAPORE – NUS Scientists Isolate Gene that Makes Plants Flower Faster.

      SINGAPORE – A*STAR, EDB Partner with Stanford University to Nurture Next-generation Asian Leaders in Medical Device Innovation.

      TAIWAN – Local University Sets Up Asia's First Animal Cancer Center.

      TAIWAN – Green Tea Might Protect Against Lung Cancer.

      TAIWAN – Embryo Screening Breakthrough to Give Healthy Babies to Parents.

      NORTH AMERICA – Scientists Develop New Stroke Therapy.

    • articleNo Access

      Feature

        Artificial Cells Containing Stem Cells for Liver Failure.

        Stem Cells and Regenerative Medicine.

        Towards a Universal Platform for Autologous Stem Cell Gene Therapy: the Induced Pluripotent Stem Cell Breakthrough.

      • articleNo Access

        Bioboard

          AUSTRALIA – Brain Gene Can Lead to Testis, Male Genitalia in Females.

          AUSTRALIA – ALSIS 2010 Heats Up Aussie Biotech.

          AUSTRALIA – World First Research on Jet Fuel Exposure Syndrome.

          AUSTRALIA – Genetic Link Found Between Spinal Arthritis and Inflammatory Bowel Disease.

          AUSTRALIA – Superbug in Melbourne.

          AUSTRALIA – Possible Peanut Allergy Treatment Discovered.

          CHINA – Bank to Freeze Eggs of Women Cancer Patients.

          INDIA – Asia's First Biodegradable Stent.

          INDIA – Swine Flu Returns - 20 Cases in a Week.

          INDIA – Rare Double Hip Replacement in Noida.

          SINGAPORE – Hydrogel Innovation Promises Multiple Uses.

          SINGAPORE – Software Detects Genetic Mutations in Influenza.

          SINGAPORE – NCCS to Establish Peritoneal and Pelvic Cancer Center.

          OTHER REGIONS – Common Blood Test Could Detect Heart Disease.

        • articleNo Access

          EYE ON CHINA

            Scientists decode the genomic sequence of 700,000-year-old horse.

            Researchers reveal subepicardial endothelial cells working as major source for coronary arteries in embryonic ventricle wall.

            Chinese 'container hospitals' ready to deploy in Africa.

            Asian Cancer Research Group and BGI report new evidence for the genetic bases of liver cancer.

            Taiwan technology lifts biomedical collaboration.

            SIIC to provide funding to biotech projects.

          • articleNo Access

            BIOBOARD

              SINGAPORE – New Material Kills E. Coli Bacteria in 30 Seconds.

              SINGAPORE – Real-Time Imaging of Embryo Development Could Pave the Way for More Effective Human Reproduction Therapies.

              UNITED STATES – Innovative Device Allows 3D Imaging of the Breast with Less Radiation.

              UNITED STATES – BIOTRONIK Launches Smallest MR Conditional Pacing Lead Available in the United States.

              UNITED STATES – Computer App Whets Children's Appetites for Eco-Friendly Meals.

              AUSTRALIA & CHINA – Uscom Agreement with CIIC Shanghai.

              JAPAN – Chugai Announces License Agreement for Recycling Antibody SA237.

              KOREA – ORIG3N(TM) and Kangstem Biotech Announce Collaboration to Study Neural Stem Cells.

            • articleNo Access

              Machine Learning Techniques for Identifying Fetal Risk During Pregnancy

              Cardiotocography (CTG) is a biophysical method for assessing fetal condition that primarily relies on the recording and automated analysis of fetal heart activity. The quantitative description of the CTG signals is provided by computerized fetal monitoring systems. Even though effective conclusion generation methods for decision process support are still required to find out the fetal risk such as premature embryo, this proposed method and outcome data can confirm the assessment of the fetal state after birth. Low birth weight is quite possibly the main attribute that significantly depicts an unusual fetal result. These expectations are assessed in a constant experimental decision support system, providing valuable information that can be used to obtain additional information about the fetal state using machine learning techniques. The advancements in modern obstetric practice enabled the use of numerous reliable and robust machine learning approaches in classifying fetal heart rate signals. The Naïve Bayes (NB) classifier, support vector machine (SVM), decision trees (DT), and random forest (RF) are used in the proposed method. To assess these outcomes in the proposed method, some of the metrics such as precision, accuracy, F1 score, recall, sensitivity, logarithmic loss and mean absolute error have been taken. The above mentioned metrics will be helpful to predict the fetal risk.

            • articleOpen Access

              Pregnancy and Delivery of a Healthy Baby Boy from a Patient Embryo Cryopreserved for Over 18 Years: A Case Report

              Cryopreservation offers semipermanent embryo storage. Although there have been various reports on effects of cryopreservation, there are few regarding preservation for 10 years or more. Here, we describe the delivery of a healthy child to a mother 51 years old, using an embryo cryopreserved for 18.3 years. The patient had four cleaved embryos cryopreserved when she was 32 years old. After more than 18 years, a Day-3, 10-cell stage embryo was transferred during a hormone replacement therapy cycle. The patient became pregnant and gave birth to a healthy boy (3,046 g). This case demonstrates the potential for live births at advanced maternal age by cryopreserving embryos at a young maternal age. To our knowledge, this is the longest cryopreservation period reported for a birth involving transfer of the mother’s own frozen embryo.

            • articleOpen Access

              #81 : Result of Non-Invasive Preimplantation Genetic Testing for Aneuploidy in Different Culture Medium Condition

              Background and Aims: Non-invasive preimplantation genetic testing (niPGT-A) emerged from the discovery of embryonic DNA in spent embryo culture medium. Many studies have been developed in order to replace Preimplantation Genetic Testing (PGT) in assisted reproductive clinic, however the results between each study varies. We hypothesized that the condition of culture medium is one of the key factors that rely on. The aim of this study is to compare the niPGT-A result between single step culture medium (SCM) and two step culture medium (TCM).

              Method: We conducted a cross-sectional study to compare the niPGT-A result between SCM and TCM with tropectoderm (TE) biopsy performed on day 5/6 as a gold standard for chromosomal analysis. The embryo was individually cultured in a 20 uL volume of cuture medium, for SCM group we used Sage one step culture medium from D1 to D5. For TCM group we used Cleav culture medium from D1 to D3 followed by Blast medium until D5. In day 5/6 we performed TE biopsy, and the embryo was freezing, then we took the spent blastocyst medium (SBM). A total 240 samples of SCM, TCM and TE were screened for chromosomal abnormality by Next Generation Sequencing (NGS) method.

              Results: The amplification rate of SCM and TCM groups was both 100% with average DNA yield of 18.1 ng/uL and 25.2 ng/uL, respectively. We validated these results by comparing chromosome status of blastocyst stage embryos as the standard, SCM group have 98.4% sensitivity and 79.4% specificity meanwhile for TCM group chromosomal status assessment using SBM had sensitivity of 85% dan specificity of 70%.

              Conclusion: The results found report successful amplification, high agreement rates and good sensitivity and specificity of the culture medium analysis. We can conclude that the time the embryo remains in contact with the culture medium favored the results.

            • chapterNo Access

              The Effects of Cancer Therapy on Gonadal Function and Fertility

              Effective treatment and survival are the prime focus of oncologists and patients with cancer. With longer survival for many patients, the preservation or restoration of the opportunity to have biological children is an important aspect of their management. Impaired fertility can be the result of the cancer or its treatment. In women delay in the opportunity to conceive caused by cancer or treatment may be a significant contribution to their distress. Adult males have the option of sperm cryopreservation, but this may not be possible for adolescent boys and is not available for pre-pubertal boys. Embryo cryopreservation is the most successful option for women with a male partner. Mature oocyte or ovarian tissue cryopreservation currently provides only a slim opportunity of a later pregnancy for single women and prepubertal girls.