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In this paper, we propose a new approach to classify emotional stress in the two main areas of the valance-arousal space by using bio-signals. Since electroencephalogram (EEG) is widely used in biomedical research, it is used as the main signal. We designed an efficient acquisition protocol to acquire the EEG and psychophysiological. Two specific areas of the valence-arousal emotional stress space are defined, corresponding to negatively excited and calm-neutral states. Qualitative and quantitative evaluation of psychophysiological signals have been used to select suitable segments of EEG signal for improving efficiency and performance of emotional stress recognition system. After pre-processing the EEG signals, wavelet coefficients and chaotic invariants like fractal dimension, correlation dimension and wavelet entropy were used to extract the features of the signal. So, by using independent-sample T-Test and Linear Discriminate Analysis (LDA), effective features are selected. The results show that, the average classification accuracy were 80.1% and 84.9% for two categories of emotional stress states using the LDA and Support Vector Machine (SVM) classifiers respectively. We achieved an improvement in accuracy, in compared to our previous studies in the similar field. Therefore, this new fusion link between EEG and psychophysiological signals are more robust in comparison to the separate signals.

Traditional Chinese Medicine (TCM) modernization has been proposed for many years, but the progress is still slow due to both ideological and technical obstacles. When I went to Japan in 1989, I found Japan has made a great progress on TCM by using modern technology. Therefore, I have studied a fine extract prepared from medicinal herbs (renamed Yi-Zhi-Yi-Shou, YZYS), a prescription of Dowager Cixi’s Yanling-Yishou-Dan of Qing Dynasty, with the current drug investigation strategies. I examined its antioxidant activity both in vitro and in vivo. The in-vitro studies found that YZYS possesses strong antioxidant capacity, such as scavenging various kinds of free radicals, and inhibits free radical-induced peroxidation of brain homogenate, microsomes, mitochondria, amino acids, deoxyribose and DNA. The in-vivo study with immobilization-induced emotional stress in rats, showed that YZYS effectively inhibits stress-induced stomach ulcers and oxidative damage in plasma and the brain. In addition, YZYS is shown to be non-toxic in both acute and chronic toxicity tests. These studies demonstrate that YZYS is a potent natural antioxidant and offer theoretical evidence for the beneficial effect of YZYS on health and brain functions, and that TCM prescriptions can be studied scientifically as modern medical drugs.