Let XX be an nn-dimensional complex Fano manifold (n≥3)(n≥3). Assume that XX contains a divisor AA, which is isomorphic to a rational homogeneous space with Picard number one, such that the conormal bundle 𝒩∗A/X is ample over A. Building on the works of Tsukioka, Watanabe and Casagrande–Druel, we give a complete classification of such pairs (X,A).