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Genetic Links to Breast Cancer Uncovered.

Malaria’s Complete Genome Sequenced.

Australian Study Finds Good News for HRT.

Gene Mapping for Cancer, Heart Diseases.

Japan Sees Improvements to Research Methodology Vital.

Tall Men Susceptible to Colon Cancer.

New Study Offers Hope For Parkinson’s Disease.

Singapore Researcher Develops Hair Loss Remedy.

Twin Goats Successfully Cloned in Taiwan.

The following topics are under this section:

• ASIA-PACIFIC — Shedding Light on COVID-19 Vaccine Development
• ASIA-PACIFIC — Community-led Interventions for Improving Blood Pressure Control
• ASIA-PACIFIC — Importance of Redox Homeostasis in Potential Treatment of Disease
• ASIA-PACIFIC — Novel Processor Architecture to Solve Complex Mathematical Problems
• ASIA-PACIFIC — Uncovering Mechanisms of the Human Biological Clock
• ASIA-PACIFIC — Discovery of Healthy Stomach Stem Cells Reveals Cancer Origins
• ASIA-PACIFIC — Cataloguing Cancer “fingerprints” to Map Cancer Genomes
• ASIA-PACIFIC — Creating a Circular Economy using Greenhouse Gases
• REST OF THE WORLD — Guide for Liquid Biopsy in Individual Glioblastoma Patients
• REST OF THE WORLD — Multi-purpose use of Breast and Kidney Cancer Drugs
• REST OF THE WORLD — The Two Faces of Immune Cells
• REST OF THE WORLD — Fine Particle Air Pollution Linked to Development of Kidney Disease

Despite abundant molecular and cytogenetic evidence supporting the role of tumor suppressor genes (TSGs) in nasopharyngeal carcinoma (NPC), the specific molecular genetic basis for this cancer requires further elucidation. A functional approach utilizing monochromosome transfers of intact and truncated chromosomes was used to evaluate the ability of chromosomal regions to functionally suppress tumor growth in a nude mouse system. Resultant hybrids were analyzed by microsatellite and fluorescent in situ hybridization (FISH) techniques to confirm the success of transfer. Thus, microcell hybrids were established for chromosomes 3, 9, and 11. Tumor suppressive regions were localized to 3p21.3, 9p21, 11q13, and 11q22-23 by analyzing deletion panels of microcell hybrids for chromosome 3, by transfection studies for chromosome 9, and by analysis of tumor segregants for chromosome 11. It is clear from these functional studies that multiple tumor suppressive regions are involved in NPC development. Localizing the genes to specific chromosomal regions using this functional approach is expected to greatly facilitate the eventual identification of TSGs essential for NPC development.