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This paper analyzes the ability of different machine learning algorithms to find patterns in the levels of gene expression for the correct classification of the five different types of tumors: breast, colon, kidney, lung, and prostate. The machine learning techniques were selected according to the most used algorithms in the related works: Bayesian method, Decision Trees, and K-Nearest Neighbors. Three metrics were applied to test the performance of the classifiers: Precision, Recall, and F1-score. The results of Precision of the algorithms were 95.03% (Bayesian), 96.73% (Decision Trees), and 99.52% (K-Nearest Neighbors). A software prototype was developed to classify tumors based on genetic expressions utilizing these three algorithms with satisfactory results.