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  • articleNo Access

    "SPATIAL-TEMPORAL" PATTERNS IN PROKARYOTE GENOMES

    We have developed a simple scheme to visualize the string composition of long DNA sequences and applied it to all available prokaryote complete genomes. Each species has a specific "portrait" and most clearly seen patterns in these portraits are determined by short avoided and under-represented strings. The "spatial" patterns in the space of short strings might reflect some "temporal" events in the evolutionary history.

  • articleNo Access

    EFFECTS OF GALACTIC GAMMA RAY BURSTS ON PLANETARY BIOSPHERES

    We examine the short-term effects that a galactic Gamma Ray Burst would cause on a planetary biosphere. The immediate environmental perturbation would arise due to the emission of an aurora like spectrum in the middle and low atmosphere, delivering at planet's surface a brief but intense ultraviolet flash. We calculated potential damages to both the photosynthetic and DNA apparatuses of unicellular organisms. We conclude that if the progenitor is 1-2 kiloparsec distant in the Milky Way, its main short-term bio-effect will be radiation damage in the photosynthetic machinery rather than in the genome.

  • articleNo Access

    Feature — Intellectual Property Strategy in Bioinformatics and Biochips

    Intellectual property rights are essential in today's technology-driven age. A strong intellectual property protection strategy is crucial in the bioinformatics and biochips technology spaces as monetary and temporal resources are tremendous in finding a blockbuster drug or gene therapy, as well as in deploying advanced biosensor and other medical systems. Current problems and intellectual property practice in the genomic space are presented and analyzed. Various strategy and solutions are proposed to guide bioinformatic and biochip companies in forming an aggressive strategy to protect one's intellectual property and competitive positioning.

  • articleNo Access

    Research Findings

      FANTOM Study Challenges Current Understanding of Genome.

      Singapore Big on Cardiovascular Research.

      Scientists Create GM Mosquitoes to Fight Malaria.

      Transgenic Zebrafish Offer New Hope for Cancer Research.

    • articleNo Access

      The Genome Institute of Singapore

      The article is a summary of the research done in GIS. It touches on the focus on systems and integrative biology and GIS's efforts in collaborating with international organizations.

    • articleNo Access

      Bioboard

        AUSTRALIA — New Meningococcal Test to Identify Genetic Predisposition

        AUSTRALIA — Scientists Discover the Double Life of Proteins

        AUSTRALIA — Gene Discovery Offers Cancer Hope

        CHINA — The American Psychiatric Association's Awards for Young Scientists Encourage Research Expertise in China

        CHINA — DuPont Partners with China to Increase Farm Productivity

        CHINA — Deadly Enterovirus Afflicts Chinese Children

        CHINA — CAS Researchers Decode Genome of Mosquito-Killing Bacterium

        CHINA — CAS, Local Governments to Jointly Set Up a Biomedical Institute in Suzhou

        CHINA — Chinese and US Scientists Map Papaya Genes

        CHINA — Genzyme to Build New R&D Center in Beijing

        INDIA — Avesthagen Launches Bioactive Teestar

        INDIA — Scientists Find Kala-azar Protein

        INDIA — Bayer Launches Disease-Resistant Hybrid Rice Arize Dhani

        INDIA — SCHOTT Forms Pharmaceutical Joint Venture in India

        INDIA — IIT Mumbai Develops Chip to Detect Myocardial Infarction

        INDIA — Tamil Nadu Plans Poison Treatment Center in Every District

        INDIA — RFCL Opens Integrated Manufacturing Plant in India

        JAPAN — Pfizer to Launch Champix® – The First Prescription Oral Smoking Cessation Aid in the Country

        NEW ZEALAND — Asthma Linked to High Fat Diet

        PHILIPPINES — Surge in Dengue Cases in the Philippines

        SOUTH KOREA — Bird Flu Outbreaks Spread in South Korea

        SINGAPORE — Edwards Lifesciences Opens Its First Heart Valve Manufacturing Facility in Singapore

        SINGAPORE — Bioimaging and Stem Cell Research in Singapore gets a Million Dollar Boost from Latest Grant Calls by A*STAR

        SINGAPORE — Maccine Receives Bio-Industry Award for Best Preclinical or Clinical CRO in Asia

        TAIWAN — New Group for Biomedical Electronics Established

        TAIWAN — Stroke Evaluation Indicator Discovered

        VIETNAM — Vietnam Bird Flu Vaccine Returns Positive Results

      • articleNo Access

        Bioboard

          AUSTRALIA – PAST Protocol to Fast-track Stroke Treatment

          AUSTRALIA – Great Potential of Regenerative Heart Tissue in Embryonic Mice

          CHINA – Babies Killed by Tainted Milk Formula Increased to Six

          CHINA – Chinese Society of Hematology and Bayer Partner to Develop Comprehensive Care Hemophilia Treatment Centers throughout China

          CHINA – Drug Information Association (DIA) Opens New Office in China

          CHINA – China Leads Way to Develop Bird Flu Pandemic Forewarning System

          CHINA – Herbal Drug Recalled after Infant's Death

          CHINA – Toddler Virus Flares Up in China Again

          CHINA – Functional Gene Discovered for Rice's Grain-Filling

          CHINA – China Tops the Health List among Developing Countries

          CHINA – U.S. Food, Drug Regulator to Set Up Offices in China

          INDIA – Maharashtra Plans Two More Biotech Parks at Khalapur, Alibag

          INDIA – Institute of Clinical Research India Partners with SingHealth

          INDONESIA – 113th Bird Flu Death Recorded in Indonesia

          JAPAN – World's First Made-to-order Bones on Clinical Trial

          JAPAN – Dioxin Tied to Metabolic Syndrome in Japan

          MALAYSIA – Medicine Study at Newcastle University in Malaysia

          NEW ZEALAND – NZ Research Implants Pig Cells in Human Diabetics

          SINGAPORE – Singapore Develops Cell Therapy Treatment for Cancer

          SINGAPORE – Singapore Sets Up Second Heart Center to Meet Demand

          SINGAPORE – Singapore is First in Southeast Asia to Offer Robotic Surgery for Gynaecologic Cancers

          SINGAPORE – SNEC Takes the Lead at the Forefront of Lasik and Corneal Transplant Technology

          SINGAPORE – Singapore Pumps Funding to Boost Dengue, Diabetes Research

          SINGAPORE – Second Case of Rare Genetic Disorder that Afflict Toddlers Detected

          SINGAPORE – Singapore Landfill Gets New Lease of Life as an Eco Park

          SINGAPORE – Fusionopolis – World Within a City – Singapore's 2nd R&D Hub

          SINGAPORE – Singapore's Stem Cell Research Signifies A Global Breakthrough

          THAILAND – Thai Scientists' First Genetic Decode Advances Thailand into “Genomic” Era

          THAILAND – Bird Flu Found in Northern Thailand, First Outbreak in 10 months

          TAIWAN – A New Food Regulatory Agency to be Set Up in Taiwan

          VIETNAM – Vietnam to Host Global Rice Meet in 2010

          VIETNAM – Liver Transplant on Vietnam's Youngest Receiver Successful

          VIETNAM – Ministries Unite For Greater Synergy to Develop Pharmaceutical Industry

          VIETNAM – Vietnam Launches Diabetes Awareness Project

        • articleNo Access

          Feature

            Interview with Kurt Wüthrich – Why Structural Biology Matters.

            The PCR Revolution – An Interview with Carl T Wittwer.

            Viva-University Children's Cancer Centre Opens at NUH.

            Biotech Crops — The Evergreen Revolution.

            From Velocity11 to Agilent Automation Solutions — The Revolutionary Road to Automation in Life Sciences.

            Schering-Plough Sets Up Translational Medicine Research Centre in Singapore.

          • articleNo Access

            Bioboard

              AUSTRALIA – Australia's First Full Genome Project to be Conducted on Corals.

              AUSTRALIA – Scientists May have Discovered New Potential Cure for Cancer.

              AUSTRALIA – First Genetically-engineered Malaria Vaccine To Enter Human Trials.

              CHINA – Lead Poisoning Sickens 600 Kids in China.

              CHINA – Groundbreaking Treatment for Oxygen-deprived Newborns.

              CHINA – China Builds First Heavy Ion Therapy Center for Cancer Patients.

              CHINA – Creating Live Mice from Skin Cells.

              INDIA – Human Clinical Trial in 2010 for Needle-free Measles Vaccination.

              INDIA – Indian Wonder Herb can Treat Male Infertility.

              JAPAN – Flood Resistant High-yield Rice Developed.

              SINGAPORE – Minimally Invasive Option for Knee Cartilage Repair.

              SINGAPORE – Novel Immunization Method for Malaria Offers Insights into Human Anti-Malaria Immune Response.

              TAIWAN – Taiwan Researchers Identify Sites of Breast Cancer Genes.

              TAIWAN – Taiwanese Researchers Develop Cell Therapy For Immunodeficiency.

              TAIWAN – Remote Healthcare Services for High-risk Patients.

              TAIWAN – Marine-derived Compounds Holds New Treatment Premise for Neuropathic Pain.

              OTHER REGIONS — UNITED STATES – New No-needle Approach to Prevent Blood Clots.

            • articleNo Access

              Bioboard

                AUSTRALIA – "Worm" Treatment for Auto-Immune Disorders.

                AUSTRALIA – New Imaging Agent for Early Diagnosis of Skin Cancer.

                AUSTRALIA – "ECG for The Mind" Fast-Tracks Depression Diagnosis in 60 minutes.

                AUSTRALIA – Seven Aussie Researchers Awarded Gates Foundation Grants.

                CHINA – Tougher Flu Control Work in Western Regions of China.

                INDIA – Drought-Tolerant Crops that can Respond to Climatic Stress.

                KOREA – Korea Raised Flu Alert for Preparedness.

                SINGAPORE – Southeast Asia's First Kilo Laboratory Opens in Singapore.

                SINGAPORE – Endow Robots with Fake Skin for that "Human Touch".

                SINGAPORE – World's First Semi-Cloned Fish.

                SINGAPORE – A Novel Fly Model of Parkinson's Disease Developed by Singapore Researchers.

                SINGAPORE – Singapore Scientists Play Key Role in Genome 10K Project.

                SINGAPORE – Findings Show H1N1 Virus No Different from Seasonal Flu.

                TAIWAN – Umbilical Cord Blood Transplant Effective in Stroke Treatment.

                TAIWAN – Adequate Folic Acid Intake Reduces Cancer Risk.

                TAIWAN – Taiwan Scientists Find Key to Immune Response.

                TAIWAN – Rice's Flood-tolerant Properties of Rice Explained.

                TAIWAN – Early Detection by Nanotechnology Eases Osteoarthritis Treatment Costs.

                EUROPE – Breakthrough Boosts Hope for Breast Cancer Treatment.

                EUROPE – The Missing Chromosome 8 Can Suppress Cancers.

                NORTH AMERICA – Access to Medical Care to Breast Cancer in Developing and Poor Nations.

                NORTH AMERICA – H1N1 Confirmed in Cat in Iowa.

                NORTH AMERICA – HIV-1 Genome Revealed.

                NORTH AMERICA – The Internet Way to Take Control of Your Health.

                NORTH AMERICA – Mold in Stale Grains Causes Cancer.

              • articleNo Access

                Research and Findings

                  Scientists Find Link between Estrogen Metabolism Pathway and Breast Cancer Risk.

                  Researchers Find Clues for Developing Biodegradable Plastics from Jatropha.

                  Discovery of Ancient Viral Invasion Important for Advancement in Regenerative Medicine.

                • articleNo Access

                  Research And Findings

                    First Genome Map of Rare, TCM Herb.

                    Gene Therapy Could Improve Parkinson's Disease.

                    Some Blind People 'See' With Ears.

                    Egg Woos Sperm with Hormone.

                    African Savanna Influenced Eye Evolution.

                    Lethal Red Tape.

                    World's First Practical Artificial Leaf.

                    Powerful Cell Motor Revealed in DNA Repair Complex.

                    Walnuts Are Top for Heart-Healthy Antioxidants.

                    Large Regional Changes in China, India Farmland Area Predicted.

                  • articleNo Access

                    INSIDE INDUSTRY

                      GTG Announces New Product Collaboration with Global Pharmaceutical Company for Companion Diagnostics in Oncology

                      NeoStem Announces Agreement with Nankai Hospital in Tianjin to Offer NeoStem's Licensed Orthopedic Technology

                      BGI and TTI GG Initiate 100 Tomato Genome Project

                      Pfizer and Shanghai Pharmaceutical Sign Memorandum of Understanding for Potential Strategic Partnership

                      Merck & Co., Inc., and Sun Pharma Sign JV for Medicines in Emerging Markets

                      Sosei Acquires Development and Commercialization Rights to Loramyc(R) from BioAlliance Pharma

                      ICON and ACRONET Sign Alliance Agreement in Japan

                      Takeda and Samyang Form Research Collaboration in Novel DDS Platform Technology for RNAi Therapeutics

                      A*STAR Scientists Partner French Pharma to Develop Anti-Cancer Drugs That Nip Breast Cancer In The Bud

                    • articleNo Access

                      EYE ON CHINA

                        Veolia Water Solutions & Technologies receives two prizes at AquaTech China for AnoxKaldnes™ MBBR technology and its Carbon Footprint Reduction Program.

                        International Consortium Led by Chinese Scientists Announce the First Complete Sequencing of Pear Genome.

                        Eli Lilly Opens Diabetes Research Center in China.

                        China 'Soaring Ahead' in Nanotechnology Research.

                        Latest Genomic Studies Shed New Light on Maize Diversity and Evolution.

                        Insight Genetics and Kindstar Global Partner to Enhance Cancer Care in China.

                        Two studies from the Institute of Plant and Microbial Biology published in PNAS show how plants respond to changing environments.

                        China's Pharmaceuticals Sales Force Levels Surpass US for First Time.

                      • articleNo Access

                        EYE ON CHINA

                          Yak genome provides new insights into high altitude adaptation.

                          Gentris and Shanghai Institutes of Preventative Medicine expand collaboration.

                          Chinese researchers identify rice gene enhancing quality, productivity.

                          Quintiles opens new Center of Excellence in Dalian to support innovative drug development.

                          BGI demonstrated genomic data transfer at nearly 10 gigabits per second between US and China.

                          Quintiles deepens investment in China - New Quintiles China Headquarters and local lab testing solution announced.

                          Beike earns AABB Accreditation for cord blood and cord tissue banking.

                          Epigenomic differences between newborns and centenarians provide insight to the understanding of aging.

                        • articleNo Access

                          BIOBOARD

                            INDONESIA – Biomed Analysis: Indonesia needs a central science fund.

                            KOREA – Agilent Technologies helps City of Daegu and Daegu Gyeongbuk Institute of Science and Technology search for biomarkers for neurological diseases.

                            SINGAPORE – New S$6.5m facility at NTU by SCELSE and Carl Zeiss to boost used water treatment and environmental life sciences engineering research in Singapore.

                            SINGAPORE – Chugai expands in Singapore with opening of second satellite research institute.

                            SINGAPORE – Rising Above the Present into the Next-Generation.

                            SINGAPORE – Austrianova Singapore announces new pancreatic cancer models.

                            SINGAPORE – IBN and Fortis Colorectal Hospital establish tissue bank for colorectal cancer research.

                            SINGAPORE – Electronic medical records progress from an enterprise-centric solution to a customer-specific application, finds Frost & Sullivan.

                            SINGAPORE – Global perspectives on Health IT from Harvard Medical School thought leader, Dr Blackford Middleton.

                            AUSTRALIA – World's first fluorescent flowers.

                            UNITED KINGDOM – AbD Serotec introduces bovine and ovine Dendritic Cell Growth Kits and antibodies.

                            USA – Medicago Successfully Completes the Production of More Than Ten Million Doses of H1N1 VLP Influenza Vaccine in One Month.

                            USA – Research validates BioNano genomics' mapping platform for complex human genome analysis.

                            USA – Nine population strategies to stop short of 9 billion.

                            USA – Virtual science libraries to be launched in Central Asia.

                            USA – Vaginal ring may help reduce HIV infections.

                          • articleNo Access

                            EYE ON CHINA

                              Forum boosts Queensland-China research partnerships.

                              Taiwan researchers develop stress-releasing lactic fermented drink.

                              Salt cress genome yields new clues to salt tolerance.

                              Shanghai scientists may have found AIDS vaccine.

                              Improved production of Acetone–Butanol–Ethanol (ABE) by genome shuffling of Clostridium acetobutylicum CICC 8012.

                              BGI debuts new tool "PDXomics™" for tumor xenograft research and applications.

                              New study sheds light on the niche divergence between related ungulates at large scale.

                              MoU signed between PAS, CAS to enhance scientific cooperation.

                              RegeneRx and Lee's reach license agreement for TB4-based products.

                            • articleNo Access

                              EYE ON CHINA

                                Biotechnology unveils secrets of Chinese medicine.

                                Climate change a mixed blessing for wheat, say experts.

                                NTOU identified germ cells and somatic cells in coral bodies for the first time in the world.

                                Researchers tabulate disturbing changes and disappearance in biodiversity in Southern Taiwan coral reefs over last 26 years.

                                NCKU research team discovers new complex in treating cancer.

                                Chinese scientists successfully crack the genome of diploid cotton.

                                Taiwan's healthcare market boosted by aging population.

                                Researchers develop mouse model of common motor neuron disease pinpointing TDP-43 protein as likely cause.

                              • articleNo Access

                                EYE ON CHINA

                                  Difference in rainfall between wet and dry seasons is increasing worldwide.

                                  Rare carbon molecule detected in dying star gives glimpse of stellar evolution.

                                  Whole genome sequencing of wild rice reveals the mechanisms underlying Oryza genome evolution.

                                  BGI and TGAC join efforts to tackle global challenges in food security, energy and health.

                                  A regeneration system for tartary buckwheat invented by CIB.

                                  A new approach for the reduction of carbon dioxide to methane and acetic acid.

                                  Launch of the Chinese-German Center for Bio-Inspired Materials at the Mainz University Medical Center.

                                  Science: The early bird loses an ovary.

                                  Disruptions of functional brain connectomes in individuals at risk for Alzheimer's disease.

                                  A breakthrough in carbohydrate-based vaccine: One vaccine targets three unique glycan epitopes on cancer cells and cancer stem cells.

                                  BSD Medical signs exclusive agreement for distribution of BSD's cancer treatment hyperthermia system in Taiwan.

                                  Catalent announces major China expansion with two new facilities.

                                • articleNo Access

                                  EYE ON CHINA

                                    Unique wine-grapes cultivation technique invented.

                                    Whole-genome sequencing unravels the puzzle of chronic mountain sickness.

                                    China eyes health research cooperation with Africa.

                                    Diamonds are for finding stem cells.

                                    Chi-huey Wong's team make advances in quest to develop carbohydrate-based vaccines.

                                    ScinoPharm Changshu teams up with Sundia MediTech.