For the month of December 2020, APBN features article contribution from variety of writers. In the Features we take a dive into how COVID-19 vaccines could be shipped worldwide in an article by Kawal Preet, President of Asia Pacific, Middle East and Africa (AMEA) region for FedEx. For the Columns section, explore the transformations in telehealth and telemedicine in the Asia Pacific region. Also, writers from ACT Genomics discuss how liquid biopsy could provide potential in replacing tissue biopsy in genomic alteration profiling. For this month in the Spotlights, are highlights from the recent APACMed Virtual Forum 2020 on how technology is changing the landscape of healthcare. Finally, Professor Nadey Hakim, a general surgeon and currently the vice president of the Royal Society of Medicine weighs in on the recent release of data on the study for Sputnik V vaccine against COVID-19.