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Several deterministic and stochastic multi-variable global optimization algorithms (Conjugate Gradient, Nelder–Mead, Quasi-Newton and global) are investigated in conjunction with energy minimization principle to resolve the pressure and volumetric flow rate fields in single ducts and networks of interconnected ducts. The algorithms are tested with seven types of fluid: Newtonian, power law, Bingham, Herschel–Bulkley, Ellis, Ree–Eyring and Casson. The results obtained from all those algorithms for all these types of fluid agree very well with the analytically derived solutions as obtained from the traditional methods which are based on the conservation principles and fluid constitutive relations. The results confirm and generalize the findings of our previous investigations that the energy minimization principle is at the heart of the flow dynamics systems. The investigation also enriches the methods of computational fluid dynamics for solving the flow fields in tubes and networks for various types of Newtonian and non-Newtonian fluids.

We analyze two theoretical approaches to ensemble averaging for integrable systems in quantum chaos, spectral averaging (SA) and parametric averaging (PA). For SA, we introduce a new procedure, namely, rescaled spectral averaging (RSA). Unlike traditional SA, it can describe the correlation function of spectral staircase (CFSS) and produce persistent oscillations of the interval level number variance (IV). PA while not as accurate as RSA for the CFSS and IV, can also produce persistent oscillations of the global level number variance (GV) and better describes saturation level rigidity as a function of the running energy. Overall, it is the most reliable method for a wide range of statistics.

In the last couple of years, quantum computing has come out as emerging trends of computation not only due to its immense popularity but also for its commitment towards physical realization of quantum circuit in on-chip units. At the same time, the process of physical realization has faced several design constraints and one such problem is nearest neighbor (NN) enforcement which demands all the operating qubits to be placed adjacent in the implementable circuit. Though SWAP gate embedment can transform a design into NN architecture, it still creates overhead in the design. So, designing algorithms to restrict the use of SWAPs bears high importance.

Considering this fact, in this work, we are proposing a heuristic-based improved qubit placement strategy for efficient implementation of NN circuit. Two different design policies are being developed here. In the first scheme, a global reordering technique based on clustering approach is shown. In the second scheme, a local reordering technique based on look-ahead policy is developed. This look-ahead strategy considers the impact over the gates in the circuit and thereby estimates the effect using a cost metric to decide the suitable option for SWAP implementation. Furthermore, the joint use of both the ordering schemes also has been explored here. To ascertain the correctness of our design algorithms, we have tested them over a wide range of benchmarks and the obtained results are compared with some state-of-the-art design approaches. From this comparison, we have witnessed a considerable reduction on SWAP cost in our design scheme against the reported works’ results.

The emissions of nitric oxide and carbon monoxide from internal combustion engines generate a large impact on the environment and on people's health. Catalytic reduction of these species using platinum group metals has already shown significant potential for emissions control. Since catalysts often use carbon monoxide to reduce nitric oxide in these devices, accurate models of their interaction are required to advance catalyst simulations in order to meet increasingly stringent emissions regulations. As a result, this paper reviews the literature of the NO–CO reaction over platinum in order to develop more precise detailed and global reaction mechanisms for use in exhaust after-treatment modeling activities. Moreover, it is found that the reaction between NO and CO over platinum yields carbon dioxide and nitrogen as main products and nitrous oxide as an important side product. Hence, this paper additionally describes the mechanism for nitrous oxide production in advance of greenhouse gas regulations.

Ocular Toxoplasmosis.

International Conference & Exhibition of the Modernization of Chinese Medicine & Health Products (ICMCM) - Annual Pivotal Event for Global Chinese Medicine Industry.

NCKU researcher develops new use of reservoir sediment.

WILEX Inc. and GeneDiagnostics Inc. enter into partnership for the IVD approval and distribution of the serum HER-2/neu test.

Celsion Corporation and Zhejiang Hisun Pharmaceutical Company enter into technology development agreement for ThermoDox® for the Greater China Territory.

SFDA grants approval for clinical studies to benapenem.

UroFlex now CE-marked; Chinese SFDA approval for Cellvizio.

China National Genebank and Smithsonian's National Museum of Natural History collaborate on biobanking to advance biodiversity research.

New analytical method for uleine alkaloids having anticancer activity.

Zhifei Biological's vaccine approved for clinical test.

EntreMed files new drug clinical trial application for ENMD-2076 with China SFDA to advance global development strategy.

Tapping on ASEAN'S Healthcare Opportunities through Singapore by Dr Derrick Tan

ASEAN – The New Playing Field for Global Medical Device Companies by Ms Cecelia Zhou

The Burden of Great Potential: the ASEAN Economic Community & Biopharmaceuticals by Dr Ross Horsburgh

Impact of the ASEAN Economic Community on the Region's Healthcare Market by Dr. Umapathy Panyala

Mundipharma and Helsinn Group Expand Exclusive Licensing and Distribution Agreements for Leading Anti-emetic Products in Middle East, Africa, Latin America and Indonesia.

Leading Regional Medical Technology Trade Associations Reinforce their Commitment to Evidence-based Healthcare.

Lonza Expands Airway Disease Portfolio with Addition of IPF Airway Cells.

Boston Scientific Launches Interventional Cardiology Online Education Portal for Physicians.

Pfizer Presented Data from PALOMA-2 Phase 3 Study Demonstrating Clinical Benefit of IBRANCE^® (palbociclib) in Asian Women with ER+, HER2- Metastatic Breast Cancer.

Global Healthcare Systems at Pivotal Point as Technology Offers Solutions to Industry Challenges – The Economist Intelligence Unit.

Cellectricon and Censo Biotechnologies Introduce a Joint Technology Access Program Utilizing High-Quality Human iPSC-based Discovery Services for CNS and Pain Research.

The following topics are under this section:

• COVID-19 and its Impact on a Global and Societal Scale
• Possible, Immediate Solution for COVID-19: A position paper
• Surviving COVID-19
• Fundamentals to Help Hospitals in ASEAN stay Resilient

In this work, we develop a simple yet robust and highly practical algorithm for constructing iterative methods of higher convergence orders. The algorithm can be easily implemented in software packages for achieving desired convergence orders. Convergence analysis shows that the algorithm can develop methods of various convergence orders which is also supported through the numerical work. The algorithm is shown to converge even if the derivative of the function vanishes during the iterative process. Computational results ascertain that the developed algorithm is efficient and demonstrate equal or better performance as compared with other well known methods and the classical Newton method.

This chapter discusses characteristics of global geostresses, including detailed descriptions of global geostress as well as that in China, the analysis of the relationship between crustal geostresses and earthquakes, and the analysis of causes and consequences of earthquakes.

This chapter discusses the major tectonic movements all over the world, including between the Mesoproterozoic and the Cenozoic eras, between the Silurian and Devonian (the first act of the Hercynian Movement including the Tianshan Movement), between the Middle and the Late Triassic, between the Jurassic and the Cretaceous, and between the Paleogene and the Neogene. In the end, the chapter touches on the evolutionary profile of representative ultra-long geological structures all over the world.

This chapter discusses evolutionary features of crustal uplifts and depressions all over the world. Global patterns can be explained as uplifts and depressions. Lands appear as a result of uplifting of the earth, whereas oceans are formed as a result of sinking. Uplifts on continents formed mountains, whereas depressions resulted in lakes or swamps. The crust evolved in this way throughout the history of the earth. There were no continental drifts or plate movements. The global crust can only be formed by the evolution of uplifts and depressions as well as that of seas and lands.

This chapter touches on evidence of land–sea changes, including local and global land–sea changes. Crustal fault activities, volcanic eruptions, and seismic activities are all manifestations of the imbalanced effects of local geostresses, which however are local phenomena of separation movements and thus cannot cause the separation of the entire crust at all. Therefore, the earth’s crust will always be a complete and indivisible whole as it was in the past.

By school years, mathematics in the classroom becomes separated from real life. However, if teachers can bring context back into mathematics, like the kids experience outside of school, math becomes real. Beginning class by teaching students a bit about what it’s like to live in another part of the world brings class alive. Global Math Stories (GlobalMathStories.org) is a resource that helps educators make cultural and global connections in the classroom. In this presentation, participants learned about the resource and explored the value of making global connections in the classroom.

Originally based upon a pregeometric model of the Universe, Process Physics has now been formulated as far more general modeling paradigm that is capable of generating complex emergent behavior. This article discusses the original relational model of Process Physics and the emergent hierarchical structure that it generates, linking the reason for this emergence to the historical basis of the model in quantum field theory. This historical connection is used to motivate a new interpretation of the general class of quantum theories as providing models of certain aspects of complex behavior. A summary of this new realistic interpretation of quantum theory is presented and some applications of this viewpoint to the description of complex emergent behavior are sketched out.

The current Communication-based Train Operation Control (CBTC) system adopts the adhesion, closed system architecture and autonomous safety model. It only makes the brakes respond to the train operation speed, train position, the input of the front-back train relationship and other input states. With the rapid development of urban rail transit, train operations are becoming more and more complex, and operators need to respond to more external events. However, since the current data acquisition equipment of CBTC system only has basic functions but has neither data acquisition nor data interface for other emergencies, the system has no response stored or is unable to respond in time for exogenous emergencies. Therefore, based on the current CBTC system, this article presents a new generation of global cooperative signaling for train control. Through increasing acquisition of external environment data acquisition equipment and interface, the safety cooperative function of wayside subsystem, carborne subsystem and other subsystem can be improved. Also, the new generation of global cooperative signaling for train control is able to have a timely and efficient response to fail-safe information. Improving the safety and reliability of train operation system brings about the fail-safe of the whole rail transit system.