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A Journey Inside the Human Body

Seward Stomacher Enables Clean and Odour Free Sample Preparation for Faecal Transplants.

SCIEX and QPS Holdings Enter Collaboration to Establish the BioBA Solution for Bioanalysis of Biologics.

Singapore Ranks 4th in How Its National Policies Impact Global Biopharma Innovation, ITIF Finds in New Analysis Marking World Health Day.

Bosch Introduces New Generation of Pure Steam Generators and Distillation Units to the Market.

Clearbridge BioMedics Partners with the ICR and The Royal Marsden to Demonstrate Label-free Approach in Isolating Heterogeneous Circulating Tumour Cells (CTCs) and PD-L1 Positive CTCs.

Treatment Brings New Hope for Patients Suffering From Fatal Lung Disease.

(Infographic): About Idiopathic Pulmonary Fibrosis (IPF).

Many biomechanical models of whole body vibrations have been developed, as part of the design, optimization, and vibrations control of vehicle seat systems, with the aim of achieving greater comfort. Most of these models are complex and result in large errors. In this paper, we introduce two new models, with and without backrest support, within a specific frequency domain. One is an optimized seven-degrees-of-freedom (7-DoF) lumped-parameter model with a unique structure to display vertical vibrations in one direction. The other is a new type of model called the coupled model, where the stiffness and damping matrices are employed instead of the spring and damper scalar parameters to present vertical vibrations in two directions — vertical and horizontal. The use of matrices not only simplifies and reduces DoF, but also gives more accurate results in comparison with the conventional multi-body models. With the help of a genetic algorithm (GA) through the global criterion method, we obtained numerical parameters of both models including mass, stiffness, and damping, which minimized the errors. The mean error for the 7-DoF model was 2.2%, while the best lumped-parameter models previously developed produced 12.6%. For the coupled model, we measured a mean error of 7%, a significant improvement over a well-known multi-body model with a mean error of 22.4%. Finally, we compared the transmissibility of vibrations in the human body applying the two models in the frequency range below 6 Hz, in both cases of with and without a backrest. These confirmed the importance of the backrest.

Finite element modeling has played a significant role in the study of human body biomechanical responses and injury mechanisms during vehicle impacts. However, there are very few reports on similar studies conducted in China for the Chinese population. In this study, a high-precision human body finite element model of the Chinese 50th percentile male was developed. The anatomical structures and mechanical characteristics of real human body were replicated as precise as possible. In order to analyze the model’s biofidelity in side-impact injury prediction, a global technical standard, ISO/TR 9790, was used that specifically assesses the lateral impact biofidelity of anthropomorphic test devices (ATDs) and computational models. A series of model simulations, focusing on different body parts, were carried out against the tests outlined in ISO/TR 9790. Then, the biofidelity ratings of the full human body model and different body parts were evaluated using the ISO/TR 9790 rating method. In a 0–10 rating scale, the resulting rating for the full human body model developed is 8.57, which means a good biofidelity. As to different body parts, the biofidelity ratings of the head and shoulder are excellent, while those of the neck, thorax, abdomen and pelvis are good. The resulting ratings indicate that the human body model developed in this study is capable of investigating the side-impact responses of and injuries to occupants’ different body parts. In addition, the rating of the model was compared with those of the other human body finite element models and several side-impact dummy models. This allows us to assess the robustness of our model and to identify necessary improvements.

A mathematical model of the stress response mechanism was constructed based on the process and characteristics of human stress response. In this model, the propagation speed of human stress hormones, the time boundary of the stress response process, and the regulatory equation of stress response are provided. An analogy is made between human stress response and ecological restoration, which have intermediary and diffusion properties between influencing factors and outcomes. Based on the human stress response mechanism model, the weights of various indicators affecting the ecological restoration effect of coal mines were calculated, and a comparison of different restoration schemes was obtained. The evaluation process and results confirm the effectiveness of applying the human stress response mechanism model.

Due to the rigor of location condition of DC earth electrode field and the difficulty of the site conditions and the difficulty of the land requisition, there may be rivers and lakes near the DC earth electrode field. In this paper, a DC pole which has a river near the DC earth electrode field is established in CDEGS, the electric field intensity and the current flowing through human body in the river are calculated, the safety of the human in the river is analyzed, and the influence of the electrical resistivity of water in the river on the electric field strength of the water is analyzed. According to the results of calculation, when HVDC system under the operation of mono-polar grounding circuit, the electric field intensity in the rivers and lakes can't meet the requirements of regulation, but it can guarantee the safety of human body, because of the difficulty of relocation, it is recommended that the land of DC earth electrode field can be enclosed in a railing and the underwater part can be enclosed in the net.