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In this study, we focused on immune stimulation by Propolis, and examined changes in the effect of irradiation after Propolis administration. We also examined the radioprotective effect of Propolis by observing its effect on the immune system. The effect of immune activation by Propolis was investigated by measuring the total immunoglobulin (Ig) G and IgM. The radioprotective effect of immune activation by Propolis was investigated by measuring the T-lymphocyte subsets in the peripheral blood of mice following whole body irradiation.

Compared with the control group, the IgG was significantly reduced in the Propolis group, indicating that Propolis suppressed IgG production. ELISA revealed that the amount of IgM in mouse serum was significantly higher in the Propolis group as compared with the control group, indicating that Propolis increased IgM production.

The number of CD4-positive cells was increased only in the Propolis group. Likewise, the number of CD4-positive cells increased by 81% in the Propolis with irradiation group compared with the irradiation group alone. Compared with the control group, the Propolis group increased CD8-positive cells. Compared with the irradiation alone group, CD8-positive cells were decreased by Propolis with irradiation group.

Propolis activated macrophages to stimulate interferon (IFN)-γ production in association with the secondary activation of T-lymphocytes, resulting in a decrease in IgG and IgM production. Cytokines released from macrophages in mouse peripheral blood after Propolis administration activated helper T-cells to proliferate. In addition, activated macrophages in association with the secondary T-lymphocyte activation increased IFN-γ production and stimulated proliferation of cytotoxic T-cells and suppressor T-cells, indicating the activation of cell-mediated immune responses.

We investigated the effect of acupuncture therapy on obese women's body weight and peripheral blood levels of serum immunoglobulin G (IgG), immunoglobulin A (IgA), immunoglobulin M (IgM), and immunoglobulin E (IgE). Sixty-three healthy women were assigned into 3 groups: placebo electroacupuncture (n = 13; mean age, 40.5 ± 4.2 years; body mass index [BMI], 33.5 ± 4.2), diet restriction (n = 23; mean age, 42.9 ± 4.0 years; BMI, 34.6 ± 2.9), and electroacupuncture (n = 24; mean age, 40.1 ± 5.9 years; BMI, 33.9 ± 2.7). Electroacupuncture was applied to the Hunger and Shen Men ear points and to the LI 4, LI 11, St 36, St 44, and Ren 6 body points for 30 min once daily for 20 days. A restricted diet of 1400 kilocalories was given to participants in all 3 groups for 20 days. Weight was lost significantly in subjects in the electroacupuncture group compared to those in the diet restriction and placebo electroacupuncture groups (p < 0.000, Tukey test). Modulations in serum IgG (p < 0.001) were apparent in women treated with electroacupuncture compared with women treated with placebo electroacupuncture and restricted diet only. No significant changes were seen in serum IgA, IgM, and IgE levels among the 3 groups. Our results suggest that electroacupuncture can be effectively used to treat obesity. We also observed a modulating effect of serum IgG, which is associated with weight loss, in patients in the electroacupuncture group.

The purpose of this study was to determine whether the precautionary measures used in the Faculty of Dentistry, University of Nuevo Leon, are adequate to prevent infection with Mycobacterium tuberculosis, taking as evidence two groups: one of 92 students of 2 °. Half have not seen patients and another group of 108 students in 9 th. and 10 °. Semesters that have served patients in different clinics of the institution. Research were conducted in two laboratory tests, the Mantoux test by inoculating 0.1 ml of PPD (purified protein derivative) to read 48 hours later, taking as positive for the one with induration of 10mm or more prior contact means with the bacillus and obtaining from them 5 mL of peripheral venous blood to perform the ELISA test for detection of latent TB blood test that analyzes the presence of IgM and IgG antibodies against extracellular proteins of Mycobacterium tuberculosis (Dr. C. Alma Yolanda Arce Mendoza). Among the groups studied, the 2 °. Semester (new entry) were found to have greater contact with M. tuberculosis than 9 °. and 10 °. Semesters when analyzing the results of the group F6, F7 and F8 where there are more students tested positive test, this equates to 29.3% and indicates infection is present. Since only two students from one hundred and eight total semesters analyzed above were positive for IgM, this equates to a rate of 1.8%. In conclusion, newly admitted students who tested positive to the tests, and had previous contact in your environment, and that means immune resistance to tuberculosis infection. Furthermore, the absence of a positive IgM test increased in the group of students from 9 th. and 10 °. Semesters, indicates that there is no danger of infection during their professional development.