The global reduction of CO2 emission generated by cars is a major challenge of the 21st century. The lightweighting of automotive structures is mandatory to achieve the ambitious environmental targets. The use of high strength steels in the car design, and especially, Press Hardened Steels (PHS) with tensile strength higher than 1000MPa, is one the most cost-efficient way to help the car makers to keep excellent crash behavior on mass saving body-in-white structures. The 2nd generation of PHS recently developed at ArcelorMittal is being deployed worldwide with Usibor®2000 and Ductibor®1000. These new grades demonstrate that CMnB metallurgies, commonly used in hot stamping, must be optimized to offer steel solutions with suitable properties for anti-intrusion and energy absorption parts. As a key metallurgical feature of these martensitic steels, a good control of inclusions and precipitations is necessary to improve the crash ductility. Among different factors influencing the bending properties of the martensitic microstructure, the present paper focuses on the effect of cleanliness of advanced steels for press hardening. The characteristics of the particles formed in the earlier stage of the steelmaking production are linked to the final In-Use Properties of the PHS. The type of particles and its geometry, such as cubic TiN, spherical complex oxides or disk-like manganese sulfides plays a different role in the crack initiation and crack propagation mechanisms. A high density of large inclusions is to be avoided as they act as local heterogeneities in the microstructure which can be detrimental to achieve a good crash performance. Particles close to the surface are even more damaging than particles localized in mid thickness. As an indirect effect, grain size refinement induced by precipitation of micro-alloying elements (Ti, Nb, V) also contributes to the achievement of a fine martensite which is essential to obtain a PHS grade with superior crash ductility. All these aspects have been integrated in the metallurgical design of Usibor®2000 and Ductibor®1000 and contribute to the remarkable and robust performances of these new PHS products.