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  • articleNo Access

    Higher arity self-distributive operations in Cascades and their cohomology

    We investigate constructions of higher arity self-distributive operations, and give relations between cohomology groups corresponding to operations of different arities. For this purpose we introduce the notion of mutually distributive n-ary operations generalizing those for the binary case, and define a cohomology theory labeled by these operations. A geometric interpretation in terms of framed links is described, with the scope of providing algebraic background of constructing 2-cocycles for framed link invariants. This theory is also studied in the context of symmetric monoidal categories. Examples from Lie algebras, coalgebras and Hopf algebras are given.

  • articleNo Access

    An analytical study of drug release kinetics from a degradable polymeric matrix

    In modern days, biodegradable polymeric matrix used as the kingpin of local drug delivery system is in the center of attention. This work is concentrated on the formulation of mathematical model elucidating degradation of drug-loaded polymeric matrix followed by drug release to the adjacent biological tissues. Polymeric degradation is penciled with mass conservation equations. Drug release phenomenon is modeled by considering solubilization dynamics of drug particles, diffusion of the solubilized drug through polymeric matrix along with reversible dissociation/recrystallization process. In the tissue phase, reversible dissociation/association along with internalization processes of drug are taken into account. For this, a two-phase spatio-temporal model is postulated, which has ensued to a system of partial differential equations. They are solved analytically with appropriate choice of initial, interface and boundary conditions. In order to reflect the potency of the advocated model, the simulated results are analogized with corresponding experimental data and found laudable agreement so as to validate the applicability of the model considered. This model seems to foster the delicacy of the mantle enacted by important drug kinetic parameters such as diffusion coefficients, mass transfer coefficients, particle binding and internalization parameters, which is illustrated through local sensitivity analysis.

  • chapterNo Access

    Chapter 7: Multinational firms, technology diffusion and trade

    Attempts to add multinational firms to the ‘new’ trade theories generate predictions about direct investment dramatically at odds with the facts. A failure to treat internalization adequately seems responsible at least in part. Empirical evidence also indicates a close association between multinational firms and knowledge capital; we exploit this to examine the role of internalization and its relation to locational factors. We model a firm which must choose between costly exporting and the possible dissipation of its knowledge capital by producing abroad. The paper examines the choice between exporting, licensing, and acquiring a subsidiary in this environment. We analyze the cost and technology parameters that support alternative modes of serving the foreign market, and we describe the international equilibrium that jointly determines the pattern of specialization and the market mode. We find that similarities in relative factor endowments may promote direct investment.

  • chapterNo Access

    Chapter 4: Multi-Layer Structure/Dynamic and Structural Capacity of Human Organizations

      The inherent micro-structure (agent-agent/system) of human organizations has been introduced in Chapters 2 and 3. Fundamentally, human organizations are composite complex adaptive systems with human beings as interacting agents (each an intrinsic complex adaptive system). This chapter further analyzes the basic conceptual foundation of the multi-layer structure, including advantages of the intelligent biotic macro-structure (with inherent features similar to that of an intelligent biological being — a structural reform), and its unique and more integrative complex adaptive dynamic in intelligent human organizations (towards iCAD). The necessity of nurturing an intelligent biotic macro-structure with vital characteristics that better synchronize and enhance sophisticated information/knowledge-related activities is highly beneficial — achieving a higher structural capacity. Thus, the attributes, functions and higher structural capacity of the more intelligent biotic macro-structure can reinforced the competitiveness of any categories of human organizations extensively.

      In this respect, connecting and engaging of intelligence/consciousness sources (individual and collective), organizing around intelligence, intelligence/ consciousness management, and the intelligent biotic macrostructure are mutually enhancing (towards higher coherency). Apparently, being intelligence/consciousness-centric is a beneficial and critical activator (strategic foundation) of the intelligence paradigmatic shift. In the present context, the roles and integration of intelligence, information and knowledge, as well as nurturing a ‘common’ language and elevating coherency in human organizations (with respect to the macro-structure and micro-structure, as well as their higher collectiveness — collectiveness capacity) must be more deeply scrutinized and utilized. The presence and significance of the individual intelligence enhancer encompassing three entities namely, intelligence, knowledge, and theory in the human thinking systems, and the necessity of nurturing a similar and effective intelligence enhancer at organizational level are analyzed. Subsequently, the supporting roles and contributions of artificial intelligence systems are also examined.

      In between the macro-structure and micro-structure are two meso-structures. In the intelligent organization theory, the complexity meso-structure encompasses spaces of complexity and punctuation points. In this respect, complexity is a highly significant focal point, and the exploitation of co-existence of order and complexity is a new necessity (complexity-centricity). Next, the network meso-structure encompassing complex network (network of networks) is also an inherent structure and dynamic in all human organizations. This meso-structure is briefly introduced, and will be more deeply analyzed with respect to governance (network-centricity, network governance).

      Hence, it is crucial to lead and manage human organizations with a strategic approach that integrates the above multi-layer structure/ dynamic at all time so that a higher structural capacity, collectiveness capacity, adaptive capacity, self-organizing capacity, and emergence-intelligence capacity can be nurtured. In the current highly competitive context, possessing these positive capabilities to elevate coherency and synergetic characteristics (including social consensus and the construal aspect) and dynamic is also highly crucial — a key focus of the complexity-intelligence strategy (towards achieving higher organizational mental cohesion). Hence, the significance and impact of nurturing intelligent human organizations with the complexity-intelligence-centric and network-centric approach that leads to the emergent of smarter evolvers and emergent strategists must be better understood and adopted. (The conceptual foundation on structural-dynamic coherency and synergy in intelligent human organizations developed in this chapter will be more deeply reviewed and exploited in later chapters.)

    • chapterNo Access

      Chapter 14: Patent protection and the composition of multinational activity: Evidence from US multinational firms

      This article examines how patent protection in developing countries affects the technology licensing strategy of US multinational firms and the associated technology transfer flows. Strengthening patent rights lowers appropriability hazards and so reduces the firms’ reliance on affiliated licensing as the more secure means of transfer (the internalization effect). However lower appropriability hazards also encourage the firms to increase the volume of technology transfer via licensing both within and outside the firm (the appropriability effect). Which effect prevails depends on the underlying technological complexity of the firms’ product. We find that a strengthening of patent protection in the host country increases the incentive to license innovations to unaffiliated parties. While unaffiliated licensing rises among all firms, the volume of affiliated licensing falls among complex-technology firms but rises among simple-technology firms. The positive appropriability effect on affiliated licensing is strong enough among simple-technology firms that the entire composition of their licensing further shifts towards affiliated parties. The results are significant for recent work on the internalization theories of multinational firms and the interaction between firm strategy and the institutional environment, as well as for patent policy in the developing world, where access to knowledge is critical.

    • chapterNo Access

      Fundamentals of Intelligent Organization Theory

        The basic foundation of the intelligent organization theory is conceptualized in this chapter. The significance of intelligence and organizing around intelligence, intelligence management and the general biotic structure of an intelligent human organization and its benefits are further discussed. The roles of intelligence, information and language in a human organization are examined. The presence and necessity of nurturing an effective intelligence enhancer encompassing three entities, namely, intelligence, knowledge and theory in the human thinking systems is introduced. The concepts on the space of order and the space of complexity are also shared. Some fundamental aspects of the deliberate strategy and emergent strategy are further examined. The above concepts are developed with respect to the fact that the human minds and human organizations are nonlinear complex adaptive systems. Consequently, the intelligent organizations that emerge are smarter evolvers.