Narrow Results

The most deadly Ebola outbreak in the history, which started in December $2013$, is currently under control. The high case fatality rate of the Ebola outbreak inspired local and international control strategies. In this paper, the dynamics of Ebola virus disease is modeled in the presence of three control strategies. The model describes the evolution of the disease in the population when educational campaigns, active case-finding and pharmaceutical interventions are implemented as control strategies against the disease. We prove the existence of an optimal control set and analyze the necessary and sufficient conditions, optimality and transversality conditions. We conclude through numerical simulations that containing an Ebola outbreak needs early and long-term implementation of joint control strategies.

Systems design utilizes top-down and bottom-up approaches to influence social or economic systems such that a desired outcome is obtained. We characterize different approaches like network controllability, network interventions, nudging and mechanism design and discuss the problems involved. We argue that systems design cannot be reduced to solving complex optimization problems.

How to make value-based care a reality?

Impactful interventions to maximise healthspan.

Viral hepatitis in Arkhangai: How Asia’s first micro-treatment program’s successes can be leveraged to treat a “silent killer”.

The long-suffering challenge of vaccination.