We study a family of “symmetric” multiparameter quantized Weyl algebras Aˉq,Λn(K) and some related algebras. We compute the Nakayama automorphism of Aˉq,Λn(K), give a necessary and sufficient condition for Aˉq,Λn(K) to be Calabi-Yau, and prove that Aˉq,Λn(K) is cancellative. We study the automorphisms and isomorphism problem for Aˉq,Λn(K) and Aˉq,Λn(K[t]). Similar results are established for the Maltsiniotis multiparameter quantized Weyl algebra Aˉq,Γn(K) and its polynomial extension. We prove a quantum analogue of the Dixmier conjecture for a simple localization (Aˉq,Λn(K))Ƶ and determine its automorphism group.