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Quasifission barriers were studied in the superheavy region 104≤Z≤126 using different projectile-target combinations. The different entrance channels parameters on quasifission barriers give an insight into the formation of compound nuclei and quasifission process. The quasifission barriers are more systematic for χm=0.25χCN+0.75χeff. The effect of compound nucleus fissility χCN and effective entrance channel fissility χeff on quasifission barriers were investigated. The quasifission barriers are strongly influenced by χCN and χeff entrance channel parameters. The detailed investigations of entrance channel parameters on quasifission barriers provide a thorough understanding of compound nuclei formation in the superheavy element in the region 104≤Z≤126. Eventually, this study helps in the selection of projectile-target combinations to synthesis of superheavy nuclei.