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  • articleNo Access

    TIME-VARYING EPIDEMIC TRANSMISSION IN HETEROGENEOUS NETWORKS AND APPLICATIONS TO MEASLES

    In this paper, we analyze some epidemic models by considering a time-varying transmission rate in complex heterogeneous networks. The transmission rate is assumed to change in time, due to a switching signal, and since the spreading of the disease also depends on connections between individuals, the population is modeled as a heterogeneous network. We establish some stability results related to the behavior of the time-weighted average Basic Reproduction Number (BRN).

    Later, a Susceptible–Exposed–Infectious–Recovered (SEIR) model which describes the measles disease is proposed and we show that its dynamics is determined by a threshold value, below which the disease dies out. Moreover, compared with models without the Exposed compartment, we can find weaker stability results. A control strategy with an imperfect vaccine is applied, to determine how it could effect the size of the peak. Due to the periodic behavior of the switching rule, we compare the results with the BRN of the model. Some simulations are given, using a scale-free network, to illustrate the threshold conditions found.

  • articleNo Access

    MATHEMATICAL MODEL OF MEASLES IN TURKEY

    In this paper, we use a previously developed measles model to forecast measles in Turkey for the period 1970–2021. We study the structural identifiability of the model both by hand and using software. By hand, we assume the prevalence and the total population size are given. Using software, we assume the incidence and the total population size are given. The model is structurally identifiable if one of the three parameters is fixed. We notice that Turkey has a significant change in time of the immigration rate and vaccination proportions, so we assume these two quantities are time-dependent. We fit the nonautonomous model to the measles incidences in Turkey for 1970–2021. We perform practical identifiability of the fitted model, and find that all parameters but one are practically identifiable. When fixing the unidentifiable parameter to a value derived from additional data, we obtain that all parameters are practically identifiable.

  • articleNo Access

    Bioboard

      AUSTRALIA – First iPS Cell Line Puts Australia in the Lead of Stem Cell Research.

      AUSTRALIA – New Treatment Hope for Prostate Cancer.

      CHINA – AIDS Is China's Top Killer Among Infectious Diseases.

      CHINA – Anti-bird Flu Drug for Human Clinical Trial Approved by China.

      CHINA – China Plans 120 Billion Dollar Health Reform By 2011.

      CHINA – 13 000 Fowl Culled in China After Bird flu.

      CHINA – China-Russia Joint Research Center.

      CHINA – Pig's Adult Stem Cells Produce Better Skins.

      CHINA – More Health Scares Amid Slowdown, Warns China.

      INDIA – Indian Experts Find Bacteria to Beat Global Heat.

      INDIA – Two Indian Firms to set up Pre-clinical Trial Units in Malaysia.

      JAPAN – Breakthrough in Universal Flu Vaccine Development.

      SINGAPORE – Taiwan Pork Banned by AVA.

      SINGAPORE – Stem-Cell Treatment For Joint Pain Gives New Hope.

      SINGAPORE – Next Generation Healthcare Information System.

      SINGAPORE – Top US University Sets up Research Centre in Singapore.

      SINGAPORE – Increase in Life-saving Umbilical Cord Donations.

      SINGAPORE – Singapore and China Scientists Report Breakthrough Research in Psoriasis.

      SOUTH KOREA – Harmful Bacteria in French Baby Formula.

      SOUTH KOREA – World's First Cloned Wolves to Test Reproductive Fitness.

      TAIWAN – Genetic Testing on the Rise.

      TAIWAN – Chinese Herbal Medicines Contain Western Drug Ingredients.

      VIETNAM – Bird Flu Strikes in Five Provinces in Vietnam.

      VIETNAM – Opening of Vietnam's First Stem Cell Bank, "MekoStem".

      VIETNAM – Hanoi Suffers Worst Measles Outbreak in Decade.

      OTHER REGIONS — EUROPE – Social Networking = Disease?

      OTHER REGIONS — EUROPE – Cancer Morbidity 'to Double in 40 Years'.

      OTHER REGIONS — NORTH AMERICA – Scientists Close in on 'Universal' Vaccine for Flu.

      OTHER REGIONS — NORTH AMERICA – Hong Kong and US Scientists Develop New Bird Flu Vaccine.

    • articleNo Access

      Bioboard

        AUSTRALIA – Australia's First Full Genome Project to be Conducted on Corals.

        AUSTRALIA – Scientists May have Discovered New Potential Cure for Cancer.

        AUSTRALIA – First Genetically-engineered Malaria Vaccine To Enter Human Trials.

        CHINA – Lead Poisoning Sickens 600 Kids in China.

        CHINA – Groundbreaking Treatment for Oxygen-deprived Newborns.

        CHINA – China Builds First Heavy Ion Therapy Center for Cancer Patients.

        CHINA – Creating Live Mice from Skin Cells.

        INDIA – Human Clinical Trial in 2010 for Needle-free Measles Vaccination.

        INDIA – Indian Wonder Herb can Treat Male Infertility.

        JAPAN – Flood Resistant High-yield Rice Developed.

        SINGAPORE – Minimally Invasive Option for Knee Cartilage Repair.

        SINGAPORE – Novel Immunization Method for Malaria Offers Insights into Human Anti-Malaria Immune Response.

        TAIWAN – Taiwan Researchers Identify Sites of Breast Cancer Genes.

        TAIWAN – Taiwanese Researchers Develop Cell Therapy For Immunodeficiency.

        TAIWAN – Remote Healthcare Services for High-risk Patients.

        TAIWAN – Marine-derived Compounds Holds New Treatment Premise for Neuropathic Pain.

        OTHER REGIONS — UNITED STATES – New No-needle Approach to Prevent Blood Clots.

      • articleNo Access

        COLUMNS

          How to make value-based care a reality?

          Impactful interventions to maximise healthspan.

          Viral hepatitis in Arkhangai: How Asia’s first micro-treatment program’s successes can be leveraged to treat a “silent killer”.

          The long-suffering challenge of vaccination.