This paper concerns the modeling of smart health sensors for data monitoring, where the data are eventually noisy, with correlated noise. In this work, we applied Clifford-based wavelets/multiwavelets for correlated noise in multi-sensors health data monitoring by estimating the set of sensor nodes minimizing an eventual error computed by the signal values at the selected nodes mostly caused by the correlated noise. Instead of directly minimizing the estimation error, we focused on evaluating a multi-level scheme based on multiwavelets for the estimation of the error between the parameter vector and its sub-vector of those nodes. Numerical simulations are provided with a comparison to some recent existing works. This model showed a performance and a fast time execution compared to those existing works. This model exceeds these models by the non-necessity to assume a priory structure of the data. Wavelets are capable to detect, localize, and eliminate the noise, even correlated, efficiently via the independent uncorrelated multiwavelets’ components.