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A prospective study of 74 patients who underwent open carpal tunnel releases was conducted, with a follow-up period of six months. We analyzed multiple preoperative variables in order to identify factors that might predict outcomes. These outcomes included improvement in symptom severity and functional severity scores, grip strength as well as patient satisfaction. All the patients showed improvement in symptoms with 72% showing complete symptomatic relief, 74% showing improvement in function and 66% showing improvement in grip strength, and 82% were either completely or very satisfied with the results of surgery. Older patients and patients with weakness were associated with poorer outcomes. Higher preoperative symptom severity and functional severity scores were also associated with less improvement in symptoms and function, respectively. This information would benefit the surgeons and patients during preoperative counseling and help facilitate the decision-making process for both parties.

Background: Several studies report that psychological factors are associated with outcomes of carpal tunnel release. However, interpretation of the association is difficult as there are diverse outcome parameters and patient expectations are different. We performed a systematic review to assess the relationships between psychological factors and the various outcome parameters.

Methods: We identified 611 papers and selected 8 papers that fit the inclusion criteria. Psychological factors assessed were anxiety, depression, pain catastrophizing, coping, and mental health status. Outcomes of interest included satisfaction and measures of perceived level of function, pain, and physical measures of recovery.

Results: For satisfaction and perceived level of function as the outcome, three studies reported a significant association, one study found an association approaching a value of significance, and one study reported no association. For pain as the outcome, two studies reported a significant association. For physical measures, one study reported no association.

Conclusions: This systematic review found that depression correlates with postoperative pain, but that the association is less clear between psychological factors and outcomes such as satisfaction, perceived level of symptom and function, and physical measures of recovery. As pain may not be a primary symptom or outcome of CTS, we consider that the current literature does not strongly support the association between psychological factors and outcomes of CTR. This review could be of benefit during preoperative counseling in patients with psychological disturbances.

The collection of outcomes data is critical for conducting clinical studies in orthopaedic surgery. Both subjective outcome data [e.g. Short Form-12 (SF-12) and Western Ontario Rotator Cuff (WORC) index] and objective data (e.g. range of motion) are necessary. Numerous studies have been conducted on the collection of patient survey data through electronic means (e.g. personal digital assistant and tablet PC), but none of these studies have made use of a device with an intuitive touch-screen interface. Studies have also been conducted on the collection of physical examination data through research-grade accelerometers but few have focused on the use of commercially available electronic devices. The goal of our project was to develop a mobile computing touch-screen system for capturing subjective and objective outcome data for the assessment of patients with rotator cuff tears. We were able to accomplish this goal through the development of a novel iPad/iPod Touch tool. Intra-rater and inter-rater reliability of shoulder flexion and external rotation measurements were good.

Background: Plantar fasciitis, the impairments include pain, changed skin blood flow (SBF) and temperature, changed plantar fascia (PF) and flexor digitorum brevis (FDB) thickness, and affected foot function index. However, the association is still unknown.

Objective: The study aimed to determine the association among pain, SBF and temperature, PF and FDB thickness, and foot function index in individuals with plantar fasciitis.

Methods: Thirty-two individuals with unilateral plantar fasciitis were interviewed for demographic data and assessed for pain at the first step in the morning (Pain${}_m$), pain at rest (Pain${}_r$), and pain at 80 N/cm² pressure (Pain${}_{80}$) by visual analog scale (VAS), SBF, and skin temperature (ST) by laser dropper flowmetry (LDF), PF and FDB thickness by ultrasound imaging (USI), and foot function by foot functional index (FFI). The association was analyzed by the Spearman correlation coefficient.

Results: A significant correlation was found among Pain${}_m$ and Pain${}_r$, Pain${}_{80}$, SBF, PF, and FFI. Pain${}_r$ was correlated with SBF, and FFI. Pain${}_{80}$ was also correlated with FFI. SBF was correlated with ST and FFI.

Conclusions: The association among pain, PF thickness, and FFI was reported in individuals with plantar fasciitis, which can be meaningful relationship between clinical outcomes and ultrasonographic evidence.

Augmentative and Alternative Communication (AAC) computer-based systems are used by individuals with severe disabilities who cannot speak. AAC technology is designed with the goal to optimize communication and improve quality of life. This paper presents principles of design based on evidence-based practice (EBP) and language activity monitoring (LAM). When applied to the research and development of AAC computer-based technology, these principles provide quantitative data for making decisions about product performance and achievable outcomes focusing on the benefit to the end-user. The evaluation of a Mandarin language software application provides an example of how the steps of EBP and LAM data were applied during the initial research tasks. The EBP model offers a unique innovation to product development by challenging computer processing designers and programmers to design systematic and scientific data collection and analysis procedures specific to EBP.

Upper extremity trauma is one of the most common types of injuries, accounting for 20 to 40 percent of injured patients presenting to the emergency department. In severe upper extremity injury, the likelihood of secondary procedures to improve function and resolve outstanding clinical problems is high. Secondary procedures are performed later than initial primary surgery, usually after wound healing and with a discernible time gap of days, weeks or occasionally longer. They should be considered as separate procedures from the primary surgery, with due diligence given to planning for it. When approaching secondary procedures, the key principles are anchored in early preparation, patient engagement, optimal timing and sequencing, reviewing and considering alternatives, and finally knowing when to stop. Although secondary procedures after upper extremity injuries can be a complex undertaking, the careful application of these principles and considerations will optimise outcomes.

Background: Flexor tendon injuries form a significant proportion of hand trauma presentations. Insult to the flexor tendon and surrounding sheath may lead to the formation of adhesions between these structures during the repair process. Tenolysis is a surgical release of these adhesions which requires careful consideration. This systematic review aims to report on the functional outcomes following isolated digital flexor tenolysis.

Methods: We searched four online databases in December 2019. Eligibility criteria for studies were: English language; described patients undergoing digital flexor tenolysis; reported functional outcomes such as total active motion (TAM). Five articles were included. The selected studies were of limited quality (level IV evidence).

Results: Of the final cohort 79.4% were male. Three studies reported patient age, with a mean age of 36.8 years [4 years to 58 years] in that subset. One hundred and three digits underwent flexor tenolysis only. Mean duration to surgery from the index operation or injury was 15.1 months [2.3 months–240 months]. Average follow-up from the tenolysis procedure was 18.6 months [3 months to 120 months]. Four studies assessing motion via Strickland classification reported 78.9% excellent or good outcomes. The remaining study reported 80% of patients reporting excellent or good motion as per Buck-Gramcko score. The complication rate reported was 15.3%.

Conclusions: This review found digital flexor tenolysis significantly improves ROM, however these benefits must be considered in the light of potential complications. A detailed discussion with each individual patient must occur prior to such an undertaking.

Background: Thumb and multiple finger amputations may result in a metacarpal and a metacarpal-like hand deformity. Toe-to-hand transfer is a recognised treatment strategy for this deformity but has risks and is resource intensive. The aim of this study is to conduct a systematic review of the outcomes of toe-to-hand transfer for traumatic metacarpal and metacarpal-like hand deformity in adult patients.

Methods: Multi-database searching with index and free text terms, duplicate standardised screening and extraction, and quality assessment was performed. The inclusion and exclusion criteria were prespecified. We included any randomised controlled trials, cohort studies, case-control studies, as well as interrupted time series, before and after intervention studies.

Results: Screening of 548 articles yielded 20 studies eligible that included 19 retrospective observational studies and one before and after intervention study. A total of 171 patients underwent 274 toe transfers for metacarpal and metacarpal-like hand deformity. No study compared toe-transfer to a control group or to a prosthesis. The before and after intervention study demonstrated significant improvement in activities of daily living, work, aesthetics and satisfaction. Additionally, no significant donor site morbidity occurred in the heterogenous sample. Outcomes from remaining studies at risk of bias suggest that those with a lesser severity of injury and at least two toe transfers score higher in functional tests and scoring systems.

Conclusions: There is limited confidence in the effectiveness of toe transfer for metacarpal and metacarpal-like hand deformity. The available evidence indicates that toe transfer(s) may restore acceptable function permitting activities of daily living, return to original or sedentary occupation and affords satisfaction.

Level of Evidence: Level III (Therapeutic)

Background: The standard (dorsal) cross-finger flap (CFF) is one of the common flaps used for fingertip reconstruction. There is little consensus regarding the sensory outcomes associated with this flap. In this systematic review, we evaluated objective sensory outcome parameters of patients who underwent CFF reconstruction.

Methods: This systematic review is reported using the PRISMA protocol and was registered with the International Prospective Register of Systematic Reviews. Literature search was done using the terms ‘cross-finger flap’, ‘heterodigital’, ‘finger-tip’ and ‘transdigital’. Data regarding the number of patients, follow-up duration and sensory outcomes, including 2-point discrimination (2-PD) were extracted from included studies. The analysis was performed using Microsoft Excel with MetaXL add-in software. Certainty assessment and summary of findings table was created using GRADEpro GDT.

Results: This review includes 14 studies with 301 patients. We found a statistically significant difference in static 2-PD of recipient and control fingers (pooled weighted mean difference [WMD]: 1.66; 95%CI: 0.03, 3.29; p = 0.00; I²=92%, n = 7 studies).

Conclusions: Dorsal CFF reconstruction for fingertip defect does not provide adequate sensory recovery.

Level of Evidence: Level III (Therapeutic)

Background: Open reduction and internal fixation with a plate is one of the alternative treatments for fracture–dislocation of the proximal interphalangeal (PIP) joint. However, it does not always lead to satisfactory results. The aim of this cohort study is to describe the surgical procedure and discuss the factors affecting the treatment results.

Methods: We retrospectively reviewed 37 cases of consecutive unstable dorsal fracture–dislocation of the PIP joint treated using a mini-plate. The volar fragments were sandwiched with a plate and dorsal cortex, and screws were used as subchondral support. The average rate of articular involvement was 55.5%. Five patients had concomitant injuries. The mean age of the patients was 40.6 years. Mean time between injury and operation was 11.1 days. The average postoperative follow-up duration was 11 months. Active ranges of motion, % total active motion (TAM) were evaluated postoperatively. The patients were divided into two groups according from Strickland score and Gaine score. Fisher’s exact test, Mann–Whitney U test and a logistic regression analysis were used to evaluate the factors affecting the results.

Results: The average active flexion, flexion contracture at the PIP joint, and % TAM were 86.3°, 10.5° and 80.6%, respectively. Group I included 24 patients who had both excellent and good scores. Group II included 13 patients who had neither excellent nor good scores. When the groups were compared, there was no significant relationship between the type of fracture–dislocation and the extent of articular involvement. There were significant associations between outcomes and patient age, period from injury to surgical intervention and presence of concomitant injuries.

Conclusions: We concluded that meticulous surgical technique leads to satisfactory results. However, factors, including the patient’s age, time from injury to surgery and the presence of concomitant injuries needing adjacent joint immobilisation, contribute to unsatisfactory outcomes.

Level of Evidence: Level IV (Therapeutic)

Background: Appropriate thumb function is critical as it is makes up approximately 40% of the hand's function leading to the greatest influence in activities of daily living (ADLs). Local flaps are the primary option for thumb reconstruction, of which the Moberg flap has been reported to have the added advantage of its advancement capacity relative to other flaps. This systematic review aims to describe the outcomes of the Moberg advancement flap and its associated modifications for coverage of palmar thumb defects.

Methods: Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed for the conduct of this systematic review. Medline, Embase, CINAHL and Cochrane Library were systematically searched to retrieve relevant citations. Title and abstract as well as full-text assessment were performed in duplicate. Full texts were extracted by one reviewer and data extracted was confirmed by a second. Complication rates and overall means were calculated for the appropriate outcomes.

Results: A total of 1,794 citations were retrieved; 15 papers were retained, including 169 patients. The overall mean follow-up was 28.6 months (n = 5 studies). In 136 patients, there was 100% flap viability (n = 12 studies). With regard to thumb aesthetics, 92% (59/64 patients) had favourable outcomes (n = 6 studies). No evidence of postoperative flexion contractures (n = 0/56 patients, 5 studies) was found. Cold intolerance occurred at a rate of 29.8% (n = 17/57, 4 studies) and the infection rate was 10.3% (6/58 patients, 3 studies).

Conclusions: Moberg/modified Moberg flaps are a safe option for thumb reconstruction given their associated postoperative outcome and complication profile.

Level of Evidence: Level III (Therapeutic)

Background: Total wrist replacement (TWR) is rarely done in the Asia–Pacific region. The aim of this study is to report the surgical outcomes and experience of TWR in patients with advanced arthritis.

Methods: This is a retrospective review of all TWR patients in the Department of Orthopaedics and Traumatology, Prince of Wales Hospital, Hong Kong, which is a university tertiary centre, from January 2004 to March 2023. Recorded demographic parameters include gender, age upon surgery, pathology, types of implants and follow-up period. The surgical outcome parameters include range of motion, grip strength, wrist function assessment, radiological and clinical complications and any related secondary operations. Postoperative X-ray and clinical notes were reviewed. All wrist function assessments were performed by specialised occupational therapists according to protocol.

Results: The study included a total of 12 wrists of 10 patients, all Chinese–Asian, with a mean age of 61.4 years at surgery. Larsen grade V arthritis constituted 50% and grade IV 16.7% of the patients, amongst which 33% had volar subluxation. The mean follow-up period was 97.4 months (21–205 months). The mean grip strength was 64.2% of the unaffected side. The mean postoperative Disabilities of Arm, Shoulder and Hand (DASH) score was 41.12% and patient-rated wrist/hand evaluation (PRWE) score 18.0. Complication incidence was 16.67% for loosening, 8.3% for metallosis and 8.3% for infection. One patient required conversion to total wrist arthrodesis due to metallosis. No patient suffered from dislocation, periprosthetic fracture and infection.

Conclusions: TWR is an effective and safe alternative to total wrist arthrodesis with comparable outcomes. Our series outcomes are satisfactory and in line with literature. With meticulous soft tissue release and balancing, volar subluxation can also be corrected and may not be a contraindication.

Level of Evidence: Level IV (Therapeutic)

The Buck-Gramcko (BG) technique of pollicisation has stood the test of time and provides good to excellent prehensile function in thumb hypoplasia. Proponents of the technique favour it because it provides good exposure to the palmar neurovascular structures. However, the skin flap design may occasionally lead to a ‘finger-like’ appearance with a sharp interdigital cleft and a triphalangeal form. In this report, we describe some of the important aspects of the operative technique so that the outcome is aesthetically pleasing in addition to providing good function.

Level of Evidence: Level V (Therapeutic)

Background: We aim to evaluate the impact of advanced age and sex on postoperative complications and radiographic outcomes after open reduction with internal fixation of distal radius fractures (DRF).

Methods: We conducted a retrospective chart review, including all patients who underwent open reduction with internal fixation of a DRF between 2012 and 2018 at a single level 1 trauma centre. We recorded patient age, sex, fracture classification (Arbeitsgemeinschaft für Osteosynthesefragen/Orthopaedic Trauma Association [AO/OTA]), time from injury to surgical date, surgical duration, diabetes status, tobacco use, illicit drug use, history of osteoporosis, use of adjuvants, fixation type, postoperative radiographic restoration of normal parameters and early complications including loss of reduction within 30 days postoperatively. Advanced age was defined as age greater than 60 years.

Results: A total of 521 patients underwent operative treatment – 264 males and 257 females. Males were twice as likely (23.5% vs. 10.1%; p < 0.0001) to sustain a type C3 fracture and be treated with a wrist spanning plate (5.3% vs. 0; p < 0.0001). A larger percentage of elderly patients undergoing operative treatment of DRF were female (20.2% vs. 5.7%; p < 0.0001) and females were more likely to carry a pre-injury diagnosis of osteoporosis (9.3% vs. 0%; p < 0.0001). And 100% of the elderly patients received were treated with a volar plate. The overall early loss of reduction was 7.5%. The overall complication rate was 8.2%. No differences in early postoperative complications were identified between sexes or age groups. Neither female sex nor advanced age was found to have increased risk of postoperative complications or early loss of reduction. Similar postoperative radiographic parameter measurements were obtained across groups as well.

Conclusions: Our results support the idea that operative treatment of unstable DRF in elderly patients and women is a reasonable treatment option without significant increases in early postoperative complications.

Level of Evidence: Level III (Therapeutic III)

Background: Advances in treatment philosophies and microsurgical techniques for peripheral nerve injuries (PNI) have led to improved outcomes. However, lack of standardisation in the evaluation of clinical outcomes after PNI treatment precludes the ability to compare reconstruction methods, such as nerve transfer, nerve grafting, free functioning muscle transfers and tendon transfers. To this end, our goal is to work collaboratively to establish a core outcome set to evaluate outcomes after PNI.

Methods: The protocol for this arc of work, delineated in this manuscript, consists of two phases: (1) conducting a systematic review of how outcomes are currently reported following PNI and (2) a Delphi process to gain consensus on the measures to include in the core outcome set for PNI. In the Delphi process, two online rounds will be used to gather consensus on the importance of each outcome measure. A final round will be conducted in person to discuss and resolve measures for which there is not yet consensus and to finalise the core outcomes set.

Conclusions: Through this process, a common standard for reporting outcomes after PNI will be created, facilitating collaboration and future research.

The following sections are included:

• INTRODUCTION

• FOUR KEY ELEMENTS OF A DECISION

• DECISIONS BASED ON EXTREME VALUES
  • Maximin Criterion
  • Minimax Regret Criterion

• EXPECTED MONETARY VALUE AND UTILITY ANALYSIS
  • The Expected Monetary Value Criterion
  • Utility Analysis

• BAYES STRATEGIES
  • Bayesian Approach in Forecasting Interest Rates

• DECISION TREES AND EXPECTED MONETARY VALUES
  • A Decision Tree for Testing a Drilling Site
  • A Decision Tree for Capital Budgeting
  • Utilizing Sample Information to Improve the Determination of Pricing Policy⁴

• MEAN AND VARIANCE TRADE-OFF ANALYSIS
  • The Mean–Variance Rule and the Dominance Principle
  • The Capital Market Line
  • The Capital Asset Pricing Model

• THE MEAN AND VARIANCE METHOD FOR CAPITAL BUDGETING DECISIONS
  • Statistical Distribution of Cash Flow

• Summary

• Appendix 21A Using the Spreadsheet in Decision-Tree Analysis

• Appendix 21B Graphical Derivation of the Capital Market Line

• Appendix 21C Present Value and Net Present Value
  • Present Value
  • Net Present Value

• Appendix 21D Derivation of Standard Deviation for NPV

• Questions and Problems

• Project V Project for Selected Topics in Statistical Analysis