Narrow Results

SINGAPORE – Sanofi Pasteur Launches Dengue Mission Buzz to Improve Public Awareness on 5th Asean Dengue Day

SINGAPORE – Singapore and the Republic of Korea collaborate to train MedTech Innovators

SINGAPORE – Strategic Partnership between A*STAR and Pyrobett

SINGAPORE – Engineers, Policy-Makers and Environmentalist meet to tackle Climate Change at the World Engineers Summit

SINGAPORE – Rebranding for New Growth: EmTech Singapore to EmTech Asia

SINGAPORE – Waters Introduces the New ACQUITY Arc System, Designed as a Bridge between HPLC and UPLC Methods

HONG KONG – Chinese Biotech 3SBIO launches up to $712 Million HK IPO

TAIWAN; TAIPEI – Advancement in New Treatments for Dengue: BRIM Biotechnology strategic collaboration with Johnson & Johnson Innovation

KOREA – Poor Nations Concerned about coping with MERS

KOREA – Merck and Samsung Bioepis: Pivotal Phase III studies for Rheumatoid Arthritis

UNITED KINGDOM – Surprise Split in Population of Monkey Malaria Parasite

GERMANY – Merck Serono: Innovative Fertility Technologies Gavi and Geri of Partner Genea Biomedx Receive CE Mark

BRUSSELS – EFIR–GRÜNENTHAL Grant Honors 7 Young Scientists for their groundbreaking Pain Research Ideas

AUSTRIA – Pacritinib Phase 3 Study Shows Positive Results In Patient Reported Outcomes Measuring Quality Of Life In Patients With Myelofibrosis

UNITED STATES – Repatha™: Human Monoclonal Antibody for Treating High Cholesterol

UNITED STATES – Cancer Clinical Trials Expert assists Regen Biopharma, Inc. in addressing FDA questions regarding planned immunotherapy clinical trial for breast cancer (dCellVax)

UNITED STATES – Novartis gains FDA approval for Promacta^® providing new option for children, ages 6 and older, with Chronic ITP, a Rare Blood Disorder

SINGAPORE – Agilent Technologies and A*STAR’s Bioprocessing Technology Institute Collaborate on New Bioanalytical Methodologies

Malaysia – Malaysian Scientists Published the Latest Results on Colorectal Cancer Screening Using the M2-PK Rapid Test in the Renowned Journal PLOS ONE

Japan – Panasonic’s Solar Lanterns Donated to UNDP Have Begun to be Distributed to Ebola Affected Regions

France – Carbon Capture is a Mirage for Poor Nations

Germany – apceth and University of Cologne to Join Forces on Combination Cellular Immunotherapies for Cancer

Ethiopia – New Development Financing Framework must take into account emerging Global Challenges and be Risk-Informed, says UN Development Chief

Tanzania – DIY Treatment of Malaria Nets could foil Resistant Mosquitoes

Kenya – Diabetes Screening in Kenya – ‘It Takes Only 5 Seconds’

United States & Denmark – Dislike Needles? Novo Nordisk has a Friend for You

United States – Protein Sciences Receives Approval from FDA for 2015/16 Formulation of Flublok® Influenza Vaccine

Five Prime Therapeutics Establishes Strategic Research Collaboration and License Agreement with Inhibrx for Novel GITR Antibodies

Elsevier Launches Health Library to Accelerate Patient Education, Engagement and Outcomes via Direct Access to Trusted Content

Chinese Researchers Demonstrate that Icotinib Creates Better Progression-Free Survival with Fewer Side Effects than Whole Brain Radiation in Non-Small Cell Lung Cancer Patients with Brain Metastases.

Depressed Patients Are Less Responsive to Chemotherapy.

Sanofi and JHL Biotech Announced Strategic Biologics Alliance in China.

Chinese Scientists Developed Cancer Breath Test.

BGI Opens Seattle Office for North America Expansion.

Mederi’s Stretta Therapy for GERD Approved in China.

HONG KONG NEWS – Experts Call for Urgent Multi-Stakeholders Collaboration in the Development of an Integrated Cancer Strategy to Safeguard the Sustainability of Hong Kong's Health Care System.

HONG KONG NEWS – Uni-Bio Science in Multiple Drug Co-Development Deal with Beijing Sun-Novo.

HONG KONG NEWS – Immunotherapy with Pembrolizumab Deemed Cost-Effective for Advanced Melanoma Patients in Hong Kong.

Background: Recalcitrant carpal tunnel syndrome (CTS) can present with persistent or recurrent symptoms after carpal tunnel release (CTR). A common aetiology for recurrent CTS is the development of perineural adhesions due to excess scarring. The hypothenar fat pad flap (HFPF) has been described to decrease the amount of scarring formed after revision CTR. Herein, we present a prospective evaluation of these patients.

Methods: A prospective series of consecutive patients by a single surgeon with recurrent CTS was conducted. All patients had at least 3 months follow-up. Patients received a revision open CTR with HFPF. The primary outcome was the Boston Carpal Tunnel Questionnaire (BCTQ). Secondary outcomes included pain and satisfaction on visual analogue scale, range of motion, grip strength, patient-reported outcomes and complications. Clinical outcomes were compared between preoperative and postoperative intervals using paired t-tests, with significance defined as p < 0.05.

Results: Fifteen wrists (14 patients) were recruited for the study. Patients were predominantly male (n = 9; 66%). Revision open CTR with HFPF was performed a median of 42 months (range: 4–300 months) post primary CTR. Patients demonstrated improved patient-reported outcomes with significantly improved BCTQ pain score (p < 0.01), Patient-Rated Wrist and Hand Evaluation (p < 0.01) and QuickDASH (p < 0.001). Two patients in the series reported postoperative complications; however, there was no incidence of donor site morbidity recorded.

Conclusions: Revision open CTR with hypothenar fat pad flap is associated with decreased pain, high patient satisfaction and improved functional measures compared to pre-operative status.

Level of Evidence: Level IV (Therapeutic)