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In this paper, a spatial model has been designed to study a damaged diffusive eco-epidemiological system of Tilapia and Pelican populations in Salton Sea, California, USA. The nature of different equilibrium points and the existence of Hopf bifurcations are obtained. Conditions for Turing instability caused by local random movement of populations are derived. Numerically, the presence/existence of the wave of chaos phenomena is reported. Further, we show that the contact rate between susceptible and infected Tilapia population plays an important role in the distribution of the infected Tilapia population. The results suggest that the removal of infected Tilapia at regular time duration and controlling salinity will help to restore the system which provides a perspective for conservation strategy.