Environmental regulations have turned their focus on controlling and mitigating air emissions that contribute to abundant air pollution. The primary pollutants found in air emissions from stack discharges are NOx, SOx, particulates and smog. With continued federal action by the EPA, coupled with action from state and local regulatory agencies, mitigation of air pollution containing harmful pollutants can be achieved to a certain scale. This chapter will focus on the harmful effects of sulfur dioxide (SO2), considered the most harmful intentionally discharged air pollutant to the environment. Due to its impact in the form of acid rain and, on a larger scale, ozone depletion, SO2 mitigation is a high priority. Additionally, methods and equipment used as well as being developed for use will be discussed for their ability to effectively treat stack discharges and mitigate SO2 pollution.