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  • articleOpen Access

    fNIRS STUDY OF EFFECTS OF FOOT BATH ON HUMAN BRAIN AND COGNITIVE FUNCTION

    As a nondrug complementary therapy and healthy leisure physiotherapy method, foot bath (FB) is gaining acceptance and popularity in many areas. The significance of this research is to study the close and complex connection between FB stimulation and the human brain using fNIRS neuroimaging techniques. Participants were placed under two different conditions (normal and foot bath) and instructed to perform Stroop task of color word matching. Research on the behavioral results of the subjects showed that FB can effectively regulate the efficiency of humans in the process of performing tasks in a natural state. The fNIRS findings showed that the PFC in the FB condition was weakly activated compared to the normal condition. FB can realize the natural and healthy regulation of human brain cognitive function, which will have an impact on many production activities in human daily life.

  • articleNo Access

    Using fMRI to compare the effects of benzylpiperazine with dexamphetamine — Their differences during the Stroop paradigm

    Rationale: Benzylpiperazine (BZP) has been found to increase neural activation in the dorsal striatum when compared to placebo in response to a Stroop paradigm, in addition, subjective effects have been compared to dexamphetamine (DEX). Despite their similarities, the two have not been directly compared in respect to their effects on selective attention and inhibition. Objectives: To use a double-blind placebo-controlled crossover study to compare the acute effects of BZP and DEX on executive function using functional magnetic resonance imaging (fMRI) and an event-related Stroop task. Methods: Eleven healthy participants aged 18–40 years undertook the Stroop task 90min after taking an oral dose of either BZP (200mg), DEX (20mg) or placebo. Results: BZP induced a greater increase in activation than DEX in the inferior frontal gyrus (IFG) during the Stroop task. DEX increased BOLD signal in the thalamus and decreased it in the IFG in comparison to placebo. Conclusion: Despite BZP and DEX reportedly inducing similar subjective effects, there are different patterns of neural activation. We believe this differential activity is due to pharmacological differences in their receptor binding profiles and that subsequent inhibitory effects might be due to their direct effect on dopaminergic activity.

  • articleNo Access

    ASSESSING THE IMPACT OF CONGRUENT AND INCONGRUENT STIMULUS IN STROOP TASK, USING EVENT-RELATED POTENTIALS (ERP) IN PATIENTS WITH DEPRESSION

    The main goal of this event-related potentials (ERPs) study was to assess the effects of stimulations in Stroop task in brain activities of patients with different degrees of depression. Eighteen patients (10 males, with the mean age 34.43±13.14) were asked to fill out Beck’s depression questionnaire. Electroencephalographic (EEG) signals of subjects were recorded in three channels (Pz, Cz, and Fz) during Stroop test. This test entailed 360 stimulations, which included 120 congruent, 120 incongruent, and 120 neutral stimulations. To analyze the data, 18 time features in each type of stimulus were extracted from the ERP components and the optimal features were selected. The correlation between the subjects’ scores in Beck’s depression questionnaires and the extracted time features in each recording channel was calculated in order to select the best features. Total area, and peak-to-peak time window in the Cz channel in both the congruent and incongruent stimulus showed significant correlation with Beck scores, with r=0.5984, p=0.008 and r=0.5890, p=0.01, respectively. Consequently, given the correlation between time features and the subjects’ Beck scores with different degrees of depression, it can be interpreted that in case of growth in degrees of depression, stimulations involving congruent images would produce more challenging interferences for the patients compared to incongruent stimulations which can be more effective in diagnosing the level of disorder.