When we do usual Computation in Science, especially in Metrology, we assume that we do Mathematics. This is only partly true in spite of the fact that database handling and data processing are most important indeed. The field of Measurement plus Observation is much more entangled with Mathematics. The following survey “Metrology and Mathematics” will focus on selected ideas, concepts, rules, models, and structures, each of which is of a basic mathematical nature. When doing this, it is not surprising at all that most theoretical and applicational requirements in the field can be reduced to just a few basic logical and mathematical structures. This is also true for complex processes in fields like humanity and society. Signal and System Theory (SST) supports this claim. However, such an endeavour asks for an orderly and consistent definition of quantities and processes and of their mathematical models, called signals and systems. These models represent all kinds of issues, items, and phenomena in the real world. The term model indicates the superordinate means of mathematical description, observation, and representation in Science and Technology. The question arises, what the role of Logic and Mathematics looks like in detail. The term structure will be consistently pivotal. And, as is generally known, structures are best visualised by graphical means, here called Signal Relation Graphs (SRG).