Latest Edition: Textbook of Structural Biology (2nd Edition)
This is an important textbook for undergraduate and graduate students in structural biology, chemistry, biochemistry, biology and medicine. Written by a team of leading scientists in the field, it covers all the essential aspects of proteins, nucleic acids and lipids, including the rise and fall of proteins, membranes and gradients, the structural biology of cells, and evolution — the comparative structural biology. The focus is on interesting and relevant molecular structures as well as central biology.
This comprehensive volume is richly illustrated with more than 200 color figures. So far, there has been a lack of comprehensive textbooks on structural biology that are up to date; this book is written to fill the gap. An accompanying CD contains high-resolution images that can be projected in a classroom.
Sample Chapter(s)
Chapter 1: Introduction (5,290 KB)
Chapter 2: Basics of Protein Structure (14,935 KB)
Chapter 3: Basics of Nucleic Acid Structure (25,594 KB)
Chapter 4: The Basics of Lipids and Membrane Structure (5,726 KB)
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Contents:
- Introduction
- Basics of Protein Structure
- Basics of Nucleic Acid Structure
- The Basics of Lipids and Membrane Structure
- Enzymes
- Metabolism of DNA: Replication and Recombination
- Transcription
- Protein Synthesis — Translation
- Protein Folding and Degradation
- Membrane Proteins
- Signal Transduction
- Cell Motility and Transport
- Structural Aspects of Cell–Cell Interactions
- The Immune System
- Virus Structure and Function
- Structural Biology and the Evolution of Biomacromolecules
- Appendices:
- Bonds and Energetics of Macromolecules
- Methods for Fold Comparison
- Prediction of Protein Conformation
- Assignment of Function to Proteins
- Protein Modification
- Nobel Laureates
Readership: Undergraduate and graduate students in structural biology, chemistry, biochemistry, biology and medicine.
“It is a marvelous book to learn or be reminded of all the structural information that I often want to know. At the same time it is a marvelous teaching book for new grad students or any kind of interested student. It replaces the now much older Branden and Tooze. There have now been quite a few similar kind of books, but this is as complete a book as I have seen, written in simple words, easy to follow with excellent illustrations.”
Michael Rossman
Hanley Professor of Biological Sciences
Purdue University
“This text provides a well thought out and reasonably current survey of structural biology … I enjoyed reading this book and recommend it for an advanced level class in structural biology or as a current reference text.”
Protein Crystallography Newsletter
“Overall, the quality and feel of the book is of a handsomely produced volume.”
Crystallography Reviews
Anders Liljas is emeritus professor of Molecular Biophysics at Lund University. He got his education in Uppsala and spent a postdoctoral period at Purdue University. After returning to Uppsala he became professor at Lund University 1988. He retired in 2004. His main interests are structural biology in general and enzymes and ribosomes in particular. He has also had a focus on crystallography at synchrotrons. He is a member of The Royal Academy of Sciences, Stockholm.
Lars Liljas obtained his PhD from Uppsala University. Since 2000 he is Professor of Molecular Biology at the same university. His main interest is viruses, especially the assembly of virus particles.
Jure Piskur did his research in Ljubljana, Stockholm, Canberra, Palo Alto and Copenhagen. From 2004 he is a professor of molecular genetics at the Lund University, Sweden. His main research interests cover metabolism of nucleic acid precursors, gene therapy, yeast comparative genomics and molecular evolution.
Göran Lindblom got his PhD from Lund Institute of Technology and became professor (chair) of Physical Chemistry at Umeå University 1981. He is Fellow of several scientific societies among which The Royal Swedish Academy of Sciences. He is also an F C Donder professor at University of Utrecht, The Netherlands. His main research interests are physical chemistry of lipids and their function in cell membranes, the importance of the regulation of lipid composition in membranes, and studies of lipid lateral diffusion, lateral phase separation (domain formation), and liquid crystalline phase structures that lipids form.
Poul Nissen got his PhD from Aarhus University followed by post-doctoral research at Yale University. He set up his independent research having returned to Aarhus and since 2006 he has been a professor of protein biochemistry. His main research interests are transmembrane transport proteins, ribosomes, drug discovery and interdisciplinary approaches in cell biology.
Morten Kjeldgaard is an associate professor at the Department of Molecular Biology, Aarhus University. From a background in chemistry and physics, he developed a profound interest for macromolecular crystallography and structural biology, with a special interest in protein synthesis. He spent two years as a post-doc at Yale University, involved in small-angle scattering studies on the 30S subunit. His scientific interests include crystallography, protein factors involved in protein synthesis, molecular graphics, and nucleic acid structure. He obtained his lic. scient. degree in 1990.
