This two-part multivolume set provides a comprehensive overview of current achievements in biomedical applications of nanotechnology, including stem cell based regenerative medicine, medical imaging, cell targeting, drug delivery, and photothermal/photodynamic cancer therapy. New approaches in early cancer diagnosis and treatment are introduced with extensive experimental results. In particular, some novel materials have been synthesized with new properties that are most effective in cancer therapy. Some of the key issues are also addressed with these recent discoveries such as bio safety and bio degradability, that are essential in the success of nano medicine.
An important aspect of this book set is the introduction of nanotechnology to the medical communities that are searching for new treatments of cancer. It may also break the barriers between the physical and medical sciences so that more MDs will be able to appreciate the new discoveries and establishments in medical diagnosis and therapy that will allow the effective handling of major clinical issues.
This major reference publication will be important as the field of nanomedicine has been rapidly developing with a great deal of new information. It is anticipated that the research will soon advance into the pre-clinical stage. Therefore, this reference set can serve as valuable background information for future clinical studies.
Contents:
- Noble Metal Nanoparticles for Biomedical Applications:
- Self-therapeutic Applications of Noble Metal Nanostructures (Guofang Chen)
- Noble Metal Nanoclusters (NCs): Synthesis and Biological Applications (Jun-Jie Zhu and Li-Hui Hu)
- Noble Metal Nanoparticles as SERS Tags: Fundamentals and Biomedical Applications (Laura Fabris)
- Noble Metal Nanoparticles to Probe and Alter Biological Phenomena (Debrina Jana, Sarah Unser, Ian Bruzas and Laura Sagle)
- Gold Nanoparticles for the Treatment of Malignant Gliomas (Jason Murphy, Drew Spencer, Yu Cheng and Maciej S Lesniak)
- Nanoparticles (NPs) for Biosensing Applications: Current Aspects and Prospects (Zanzan Zhu and H Susan Zhou)
- Application of Nano-Structured Materials and Devices in Chemical and Biological Sensing:
- Micro/Nanofluidic Biosensors (Zhuo Li)
- Nanomaterial-Based Surface-Enhanced Raman Scattering Sensor (Li Li)
- Inorganic Nanomaterial-Based Transistors with Application as Sensors (Xiaohan Wu and Jia Huang)
- Applications of Carbon Nanomaterials in Biosensor (Yin Zhang)
- Biochemical Sensors Based on Organic Field Effect Transistors (Weiguo Huang)
- Conjugated Polymers-Based Chemical and Biological Sensors (Diqing Su, Yingshan Yao, Yani Chen, Jiajun Peng and Ziqi Liang)
- Conjugated Polymer Nanoparticles: Preparation, Properties and Applications in Fluorescence Sensing and Imaging (Ruoyu Zhan)
- Nanostructured Porous Materials for Biosensor Application (Cong Fu and Yajun Wang)
- Nanotechnology in Gene Delivery:
- Viral and Nonviral Cancer Gene Therapy (Yongguang Yang, Marissa Leonand and Haiyun Gan)
- Adeno-Associated Virus and Vector (Chen Ling and Daniel Zhang)
- Targeted Strategies to Engineer Viral Vectors for Human Gene Therapy (Natnaree Siriwon, Yarong Liu, John Mac and Pin Wang)
- Molecular Mechanisms of Nonviral Gene Delivery (Timothy M Martin and Angela K Pannier)
- Nonviral Transfection Methods of Efficient Gene Delivery: Micro-/Nano-Technology for Electroporation (Lingqian Chang, Chi-ling Chiang, Yanli Jiao and Lesheng Teng)
- Substrate-Mediated Gene Delivery (Tadas Kasputis, Eric Farris, Gabriela Guerreiro, Jessica Taylor and Angela K Pannier)
- MicroRNA Delivery by Lipoplexes in Lung Cancer Therapy (Qixin Wang and Yun Wu)
- Nanotechnology in Gene Delivery: Pharmacokinetic and Pharmacodynamic Perspectives (Zhaogang Yang, Xinmei Wang, Xiaomeng Huang, Jing Xie and Chenguang Zhou)
- Nano Imaging: From Fundamental Principles to Translational Medical Applications:
- Gold Nanoparticles for X-ray Computed Tomography Imaging (Benqing Zhou, Jianzhi Zhu and Xiangyang Shi)
- Superparamagnetic Iron Oxide Nanoparticles for Cellular Imaging and Targeted Therapy: Opportunities and Challenges for Clinical Translation (Yi-Xiang Wang)
- Microbubbles for Biomedical Imaging (Fang Yang, Huating Cui, Tuantuan Wang, Mingxi Li and Ning Gu)
- Cd-Containing Quantum Dots for Biomedical Imaging (Jing Wang)
- Nanoparticles for Photoacoustic Imaging (Chengbo Liu, Huajuan Zhang and Liang Song)
- Nanoparticles for Multi-Modality Imaging (Ping Gong, Li Zhang, Yalin Lv, Xiaoqing Meng, Duyang Gao, Huqiang Yi, Pengfei Zhang, Zonghai Sheng, Dehong Hu, Chi Chen, Mingbin Zheng, Guanhui Gao and Lintao Cai)
- Cellular Uptake Mechanisms of Nanoparticles for Biomedical Imaging (Leshuai Zhang and Dandan Chen)
Readership: This reference set is written for a wide readership including university students and researchers from diversified backgrounds such as physics, materials science, engineering, and chemistry. Both undergraduate and graduate students will find it a valuable reference book on key topics related to nanomaterials science and technology.

Dr Donglu Shi is currently the Chair of the Materials Science and Engineering Program at the University of Cincinnati. He has been serving as the Editor-in-Chief of Nano LIFE, and Associate Editor of Materials Science & Engineering: C, and J. of Nanomaterials. He has won the Distinguished Engineering Researcher Award, the SIGMA XI Research Recognition Award, Honor Roll Professor Award, and Neil Wandmecher Teaching Award. Donglu Shi's main interests include nanostructure design for medical theranositics. The most recent works pioneer some novel approaches in biomarkerless cancer cell targeting and photothermal killing based on the surface electrical charge differences between the cancer cells and nanoparticles. He has also participated in the research on microRNA replacement therapy via a unique magnetic nano porous delivery system, which is a crucial step in genome-driven precision medicine.