This book provides a summary of the various aspects of corneal transplantation — the clinical, experimental (including multimedia display of the surgical techniques), immunological, therapeutic and prosthetic components — in one volume. The interested specialist in one field can thus have access to information from the other fields and develop a broad concept of the challenges to be faced in achieving the ultimate goal, i.e. an optically clear, visually satisfactory, functioning corneal graft which is tolerated in the long term without the need for systemic immunosuppression. A second purpose of the book is to provide information regarding current immunological concepts of the process of corneal graft rejection. In particular, recent work in the fields of innate versus adaptive immunity, novel therapeutics and corneal xenografts is presented.
Contents:
- A Brief History of Corneal Transplantation
- Surgery of Corneal Graft in Humans
- The Clinical Problem
- Eye Banking
- MHC Antigens, Tissue Typing and Blood Group Matching in Corneal Transplantation
- The Alloresponse to Corneal Graft
- The Xenoresponse to Corneal Graft
- Animal Models of Corneal Graft
- Pathology of Human Corneal Transplantation
- Therapeutic Approach to Experimental Corneal Graft Rejection
- Immunosuppression for Human Corneal Graft Rejection
- Transmission of Disease Through Corneal Transplantation
- Artificial Corneas
Readership: Researchers and practitioners in ophthalmology, optometry, immunology, transplantation and surgery.
