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Information exchange between inanimate objects (like individual physical particles, or systems) involve special approaches, due to the peculiarity that conscious information emitters/recipients are excluded. This paper aims at answering a part of questions arising by these approaches. One can put the question, whether can we speak about physical information when there is no live percipient to accept, evaluate and use it? Can one speak about physical information (e.g., signal exchange) between inanimate physical objects? (Cf., e.g., Feynman diagrams.) If so, what is the nature of that information? Is (physical) information a passive phenomenon, or its existence presumes activity? What does, e.g., a signal represent if it is not perceived and used at another end, and where is that end when one can say: that signal was lost without perception or use? I try to illustrate my personal answers with a few examples quoted from the history of 20th century physics. My answers to the questions are not intended to be enunciations and to provide final solutions, rather they serve as arguments and indicate that nothing is closed, the discussion is open.