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Ethnobotany, Phytochemistry and Pharmacological Properties of Eucommia ulmoides: A Review

National & Local United Engineering Laboratory of Integrative Utilization Technology of Eucommia Ulmoides, College of Hunan Province, Jishou University, Jishou 416000, P. R. China

College of Biological Resources and Environmental Sciences, College of Hunan Province, Jishou University, Jishou 416000, P. R. China

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Li Tang

National & Local United Engineering Laboratory of Integrative Utilization Technology of Eucommia Ulmoides, College of Hunan Province, Jishou University, Jishou 416000, P. R. China

College of A & F Science and Technology, Hunan Applied Technology University, Changde 415000, P. R. China

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Jian-Wu He

National & Local United Engineering Laboratory of Integrative Utilization Technology of Eucommia Ulmoides, College of Hunan Province, Jishou University, Jishou 416000, P. R. China

College of Biological Resources and Environmental Sciences, College of Hunan Province, Jishou University, Jishou 416000, P. R. China

Key Laboratory of Plant Resources Conservation and Utilization, College of Hunan Province, Jishou University, Jishou 416000, P. R. China

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Jing Li

National & Local United Engineering Laboratory of Integrative Utilization Technology of Eucommia Ulmoides, College of Hunan Province, Jishou University, Jishou 416000, P. R. China

College of Biological Resources and Environmental Sciences, College of Hunan Province, Jishou University, Jishou 416000, P. R. China

Key Laboratory of Plant Resources Conservation and Utilization, College of Hunan Province, Jishou University, Jishou 416000, P. R. China

E-mail Address: lkg1220@126.com

Correspondence to: Prof. Jing Li, College of Biological Resources and Environmental Sciences, Jishou University, 120, People Road South, Jishou 416000, P. R. China. Tel: (+86) 743-856-4416, Fax: (+86) 743-856-4416.

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, and

Yuan-Zhong Wang

National & Local United Engineering Laboratory of Integrative Utilization Technology of Eucommia Ulmoides, College of Hunan Province, Jishou University, Jishou 416000, P. R. China

Institute of Medicinal Plants, Yunnan Academy of Agricultural Sciences, Kunming 650200, P. R. China

E-mail Address: boletus@126.com

Correspondence to: Dr. Yuan-Zhong Wang, Institute of Medicinal Plants, Yunnan Academy of Agricultural Sciences, 2238, Beijing Road, Panlong District, Kunming 650200, P. R. China. Tel: (+86) 871-6503-3575, Fax: (+86) 871-6503-3441.

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https://doi.org/10.1142/S0192415X19500137Cited by:107 (Source: Crossref)

Abstract

Eucommia ulmoides Oliver, a single species of Eucommia genus belonging to the Eucommiaceae family, is an endemic in China and has been used in traditional Chinese medicine for nearly two thousand years. Records from different historical periods highlight E. ulmoides and its officinal botanical parts, usefulness in adaptation to disease and its central role in Chinese medicine theory. There are also historical collection documents for minorities in China. Tearing the leaves, bark and fruit produces strands of latex; a description of E. ulmoides’s morphological features is recorded in this paper. This review summarizes 204 natural compounds isolated from this plant, which are divided into seven categories: lignans, iridoids, flavonoids, phenols, steroids, terpenes and others. These components possess wide-ranging pharmacological efficacies, such as antihypertensive, antihyperglycemic, antihyperlipidemia, anti-oxidative, anti-osteoporosis, antitumor, immunomodulatory and neuroprotective activities. This review aims to provide a reference for extensive researches of E. ulmoides crude drugs, especially for quality control, biosynthesis and structure modification of active ingredients and pharmacological mechanism.

Keywords:

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