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The Application of Fermentation Technology in Traditional Chinese Medicine: A Review

Lin Li

School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, P. R. China

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Li Wang

School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, P. R. China

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Wenxiang Fan

School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, P. R. China

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Yun Jiang

Sichuan Neautus Traditional Chinese Herb Limited Company, Chengdu 611731, P. R. China

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Chao Zhang

Sichuan Neautus Traditional Chinese Herb Limited Company, Chengdu 611731, P. R. China

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Jianghua Li

Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610052, P. R. China

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Wei Peng

School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, P. R. China

E-mail Address: pengwei002@126.com

Correspondence to: Prof. Wei Peng, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, 1166 Liutai Avenue, Wenjiang District, Chengdu 611137, P. R. China. Tel: (+86) 28-6180-1001.

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, and

Chunjie Wu

School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, P. R. China

E-mail Address: wucjcdtcm@163.com

Correspondence to: Associate Prof. Chunjie Wu, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, 1166 Liutai Avenue, Wenjiang District, Chengdu 611137, P. R. China. Tel: (+86) 28-6180-1001.

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https://doi.org/10.1142/S0192415X20500433Cited by:97 (Source: Crossref)

Abstract

In Chinese medicine, fermentation is a highly important processing technology whereby medicinal herbs are fermented under appropriate temperature, humidity, and moisture conditions by means of the action of microorganisms to enhance their original characteristics and/or produce new effects. This expands the scope of such medicines and helps them to meet the stringent demands of clinical application. Since ancient times, Chinese medicine has been made into Yaoqu to reduce its toxicity and increase its efficiency. Modern fermentation technologies have been developed on the basis of traditional fermentation techniques and modern biological technology, and they can be divided into solid fermentation, liquid fermentation, and two-way fermentation technologies according to the fermentation form employed. This review serves as an introduction to traditional fermentation technology and its related products, modern fermentation technologies, and the application of fermentation technology in the field of Chinese medicine. Several problems and challenges facing the field are also briefly discussed.

Keywords:

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