Generalized language-of-thought arguments, appropriate, in the sense of Dretske, to interacting cognitive modules, permit exploration of how disease states interact with medical treatment, given an embedding context of structured psychosocial stress. The interpenetrating feedback between treatment and response creates a kind of idiotypic hall of mirrors generating a synergistic pattern of efficacy, treatment failure, adverse reactions, and patient noncompliance which, from a Rate Distortion perspective, embodies a distorted image of externally-imposed structured stress. For the US, accelerating spatial and social spread of such stress enmeshes both dominant and subordinate populations in a linked system of pathogenic social hierarchy which will express itself, not only in an increasingly unhealthy society, but in the diffusion of therapeutic failure, including, but not limited to, drug-based treatments.