A four-stage operational transconductance amplifier (OTA) with a novel compensation structure combining multipath Gm-C compensation and no capacitor feed-forward compensation is proposed in this paper. Based on the small-signal model, stability analysis and design consideration are carried out to demonstrate the stability of the compensation technique. To verify the effectiveness of the compensation scheme, the proposed OTA which drives a 2 pF capacitance, is simulated in TSMC 65nm 1.2V CMOS process, achieving 808MHz gain-bandwidth, 119dB DC gain, 585V/μs slew rate (SR) and 6 ns 1% settling time. The circuit is operated at the single supply voltage of 1.2V with power consumption of 2.17mW and the layout area is 0.011mm2.